2-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-7-(2-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one CAS 1242974-77-1
| CAS No. | 1242974-77-1 |
| Molecular Formula | C23H20Cl2N4OS |
| Molecular Weight | 471.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 471.40 g/mol gives 2-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-7-(2-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-7-(2-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1242974-77-1), molecular formula C23H20Cl2N4OS and molecular weight 471.40 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C23H20Cl2N4OS, 2-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-7-(2-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 471.40 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20Cl2N4OS |
| Molecular Weight | 471.40 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-7-(3-chlorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1242864-74-9)
- 4-Chloro-N-(1-(5-((2-chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)ethyl)benzenesulfonamide (CAS 338954-02-2)
- (E)-[(2-Chloro-6-fluorophenyl)methoxy][(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)methylidene]amine (CAS 478079-39-9)
- 3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one (CAS 337921-03-6)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy}-1-[(1Z)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]urea (CAS 338396-80-8)
- N-[(3-Chloro-4-methoxyphenyl)methyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 478249-55-7)
- 4-chloro-6-({5-[3,5-di(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-2-(methylthio)pyrimidine (CAS 680217-14-5)
- 5-Chloro-N-(2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)-4-(3-nitrophenoxy)pyrimidin-2-amine (CAS 1213269-25-0)
Recommended Standards
- 7-(3,4-Dichlorophenyl)-2-[4-(3-methylphenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1251646-25-9)
- tert-butyl (4S)-3-bromo-4-(tert-butoxycarbonylamino)spiro[4,6-dihydropyrrolo[1,2-b]pyrazole-5,4'-piperidine]-1'-carboxylate (CAS 2843690-96-8)
- 6,8-Dichloro-3-(2,6-dimethylphenyl)-2-(((4-methoxyphenyl)thio)methyl)quinazolin-4(3H)-one (CAS 338957-61-2)
- 4-Bromo-4'-phenyl-9,9'-spirobi[fluorene] (CAS 2102016-85-1)
- 5-(sec-Butylthio)-1,3,4-thiadiazole-2-thiol (CAS 19921-51-8)
- 4-Cyclopropyl-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 869945-40-4)
- N-heptylformamide (CAS 59734-16-6)
- trans-4-(4-N-Boc-piperazin-1-yl)tetrahydrofuran-3-ol (CAS 1346660-42-1)
- (Z)-1-Carbamoyl-N-phenylmethanecarbonimidoyl cyanide (CAS 400082-55-5)
- Methyl 2-(chlorosulfonyl)-2-methylpropanoate (CAS 55896-98-5)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-methoxypyridine-4-methanol (CAS 1361756-41-3)
- Tert-butyl 4-(cyclobutanecarboxamido)piperidine-1-carboxylate (CAS 1197980-74-7)
- Tert-butyl (S)-3-(hydroxymethyl)-2-azabicyclo[2.2.2]Octane-2-carboxylate (CAS 1251022-42-0)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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