3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one CAS 337921-03-6
| CAS No. | 337921-03-6 |
| Molecular Formula | C17H10Cl2F6N4O |
| Molecular Weight | 471.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one (CAS 337921-03-6), a certified reference material (molecular formula C17H10Cl2F6N4O, MW 471.18 g/mol) for analytical method development and quality control.
Structurally, 3-Chloro-1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-6-(trifluoromethyl)-1,2-dihydroquinoxalin-2-one (C17H10Cl2F6N4O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 471.18 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H10Cl2F6N4O |
| Molecular Weight | 471.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- (E)-[(2-Chloro-6-fluorophenyl)methoxy][(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)methylidene]amine (CAS 478079-39-9)
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- 2-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-7-(2-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1242974-77-1)
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Recommended Standards
- (2Z)-N-(4-Bromophenyl)-2-[(1E)-{[(2,4-dichlorophenyl)methoxy]imino}methyl]-3-(dimethylamino)prop-2-enamide (CAS 320417-96-7)
- N-(2-(2,2-dichloroacetamido)ethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-73-2)
- N-(2-Aminobenzo[d]thiazol-6-yl)-2-(2,4-dibromo-6-methylphenoxy)acetamide (CAS 1706448-51-2)
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- 1-Cyano-N,N,N-trimethylmethanaminium iodide (CAS 82272-28-4)
- 1208075-11-9 4-Bromo-3,5-difluoro-N-methylaniline MFCD11655720 (CAS 1208075-11-9)
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