1-(2-Chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylic acid CAS 1243023-71-3
| CAS No. | 1243023-71-3 |
| Molecular Formula | C18H13ClFNO4 |
| Molecular Weight | 361.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
1-(2-Chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylic acid (CAS 1243023-71-3), molecular formula C18H13ClFNO4 and molecular weight 361.75 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C18H13ClFNO4, 1-(2-Chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylic acid contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 361.75 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H13ClFNO4 |
| Molecular Weight | 361.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (2R,3S,4R)-4-(Benzyloxy)-2-(hydroxymethyl)-3,4-dihydro-2H-pyran-3-ol (CAS 58871-08-2)
- 5-Methylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011363-90-8)
- 4-Methyl-2-(1H-pyrazol-1-yl)-1H-benzo[d]imidazole (CAS 40341-06-8)
- Methyl 4-Bromothiophene-3-carboxylate (CAS 78071-37-1)
- ZL0420, >98% (HPLC) (CAS 2230496-80-5)
- 2-azaspiro[3.3]heptan-5-ol hydrochloride (CAS 2173991-60-9)
- (S)-2-(4-(5,6,7,8-tetrahydroquinolin-8-ylamino)butyl)isoindoline-1,3-dione (CAS 558444-72-7)
- Fmoc-Lys(Boc)-Pro-OH (CAS 130445-10-2)
- (E)-[1-(4-Methyl-2-phenyl-1,3-thiazol-5-yl)ethylidene]amino 3-methylbenzoate (CAS 860649-88-3)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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