3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)-2,5-dihydrothiophene 1,1-dioxide CAS 338407-01-5
| CAS No. | 338407-01-5 |
| Molecular Formula | C10H7ClF3NO4S2 |
| Molecular Weight | 361.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)-2,5-dihydrothiophene 1,1-dioxide.
3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)-2,5-dihydrothiophene 1,1-dioxide (CAS 338407-01-5), molecular formula C10H7ClF3NO4S2 and molecular weight 361.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)-2,5-dihydrothiophene 1,1-dioxide (C10H7ClF3NO4S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 361.75 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)-2,5-dihydrothiophene 1,1-dioxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClF3NO4S2 |
| Molecular Weight | 361.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chloro Standards
- 1-(2-Chloro-4-fluorobenzyl)-3-formyl-6-methoxy-1H-indole-2-carboxylic acid (CAS 1243023-71-3)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3-methoxypropyl)-1H-pyrrole-2-carboxamide (CAS 338397-69-6)
- 4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate (CAS 740081-22-5)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2-(cyclopropylmethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860789-13-5)
- 7-Chloro-5-(2-Fluorophenyl)-3-Methyl-2-(Nitromethylene)-2,3-Dihydro-1H-1,4-Benzodiazepine-4-Oxide (CAS 59469-63-5)
- 7-Chloro-5-fluoro-2-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3-benzoxazole (CAS 866010-51-7)
- N-[(4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl)carbonyl]-N'-(4-fluorophenyl)urea (CAS 650615-82-0)
- 3-[(2-Chloro-6-fluorophenyl)methyl]-1-[(4-fluorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (CAS 477856-18-1)
Recommended Standards
- N-(1-(tert-Butyl)-4-(5-chloro-2-hydroxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide (CAS 1958100-69-0)
- Efavirenz Impurity 7 (CAS 211563-41-6)
- Gefitinib Impurity 6 (CAS 788136-89-0)
- 5-Bromo-6-chloro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2412348-14-0)
- Methyl 2-(1-(morpholine-4-carboxamido)cyclohexyl)acetate (CAS 1573547-40-6)
- 5-Hydroxytetrahydro-2H-pyran-2-carboxylic acid (CAS 1822587-33-6)
- 3-Bromo-4-chloro-8-(trifluoromethyl)quinoline (CAS 1204812-14-5)
- 2-(tert-Butyl)-5-isopropyl-1H-indole (CAS 906765-98-8)
- 1-amino-1-(2-methyl-1,3-thiazol-4-yl)propan-2-ol dihydrochloride (CAS 1909319-96-5)
- 4-(Difluoromethyl)-6-fluoropicolinonitrile (CAS 1806782-97-7)
- Avanafil Impurity 43 (CAS 330785-81-4)
- [(2R,4R)-4-methoxypyrrolidin-2-yl]methanol (CAS 1032048-72-8)
- 4-((Diethylamino)methyl)-5-ethylfuran-2-carboxylic acid hydrochloride (CAS 1052532-17-8)
- Peptide 436 (CAS CATO-CPTD788436)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com