7-(2-Chlorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one CAS 1243085-32-6
| CAS No. | 1243085-32-6 |
| Molecular Formula | C22H18ClFN4OS |
| Molecular Weight | 440.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-(2-Chlorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1243085-32-6), molecular formula C22H18ClFN4OS and molecular weight 440.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-(2-Chlorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one (C22H18ClFN4OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7-(2-Chlorophenyl)-2-[4-(4-fluorophenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H18ClFN4OS |
| Molecular Weight | 440.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 7-(4-Chlorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1226430-85-8)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-7-(3-fluorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1243004-67-2)
- 2-(4-(2-Chlorophenyl)piperazin-1-yl)-7-(3-fluorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1243061-78-0)
- 7-(3-Chlorophenyl)-2-[4-(2-fluorophenyl)piperazin-1-yl]-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1243089-53-3)
- 7-(2-Chlorophenyl)-2-(4-(2-fluorophenyl)piperazin-1-yl)thieno[3,2-d]pyrimidin-4-ol (CAS 1243104-77-9)
- 3-{1-[2-(2-chlorophenyl)acetyl]piperidin-4-yl}-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775559-69-7)
- 3-(4-Chlorophenyl)-5-(4-phenylpiperazin-1-yl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 338793-00-3)
- 2-((2-(4-Chlorophenyl)-2-oxoethyl)thio)-4,6-diphenylnicotinonitrile (CAS 94360-91-5)
Recommended Standards
- 3-{1-[2-(3-chloro-4-methoxyphenyl)acetyl]piperidin-4-yl}-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775357-95-3)
- 4-(((6-Amino-3-(4-chlorophenyl)pyrido[2,3-b]pyrazin-8-yl)amino)methyl)benzenesulfonamide (CAS 28643-00-7)
- 3-{1-[2-(4-chloro-2-methylphenoxy)acetyl]piperidin-4-yl}-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775547-10-8)
- 1,1',1''-(Benzene-1,3,5-triyl)tris(2-bromoethanone) (CAS 38460-56-9)
- 1-Bromothianthrene (CAS 94522-76-6)
- 6-Tosyl-1-oxa-6-azaspiro[3.3]Heptan-3-ol (CAS 1349199-64-9)
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- N-methoxy-N-methyl-2-(2-oxopyrrolidin-1-yl)acetamide (CAS 388630-70-4)
- 1-(4-Ethoxyphenyl)-2,4-dimethyl-1H-pyrrole (CAS 100717-62-2)
- ilexgeninA (CAS 108524-94-3)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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