Benzyl 5-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate CAS 1243328-71-3
| CAS No. | 1243328-71-3 |
| Molecular Formula | C21H21F3N2O2 |
| Molecular Weight | 390.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Benzyl 5-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Benzyl 5-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1243328-71-3), a certified reference material (molecular formula C21H21F3N2O2, MW 390.40 g/mol) for analytical method development and quality control.
Benzyl 5-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate (C21H21F3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Benzyl 5-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1'-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H21F3N2O2 |
| Molecular Weight | 390.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Benzyl Standards
- 1-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazine (CAS 22365-08-8)
- 4-[3,5-Bis(trifluoromethyl)phenyl]-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (CAS 1170510-97-0)
- 3-[2,5-bis(trifluoromethyl)phenyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 722465-84-1)
- 4,4-Bis(trifluoromethyl)-5,5,6,6,7,7,7-heptafluorohept-2-enoic acid (CAS 261503-43-9)
- 2-({2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}sulfanyl)-4-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 400077-06-7)
- 2-({2-oxo-2-[4-(trifluoromethyl)phenyl]ethyl}sulfanyl)-4-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 400079-37-0)
- Methyl 2-({2-[2-(trifluoromethyl)-1H-1,3-benzimidazol-1-yl]propanoyl}amino)benzenecarboxylate (CAS 692732-71-1)
- 6-Phenyl-3-((3-(trifluoromethyl)phenyl)amino)-5,6,7-trihydro1H-indazol-4-hydrazone (CAS 1159976-61-0)
Recommended Standards
- H-Val-Gly-Ser-Glu-OH (CAS 61756-22-7)
- (4-(3,5-Difluorophenyl)-1,1-dioxido-4H-benzo[b][1,4]thiazin-2-yl)(pyrrolidin-1-yl)methanone (CAS 1251698-75-5)
- Thiencarbazone-Methyl (CAS 317815-83-1)
- (4S)-3-[(2R)-2-[(2R)-2-(2,4-Difluorophenyl)oxiranyl]-1-oxopropyl]-4-benzyl-2-oxazolidinone-d3 (CAS 1329641-35-1)
- Tert-butyl 2-oxo-2,5,6,8-tetrahydro-1,7-naphthyridine-7(1H)-carboxylate (CAS 1770824-50-4)
- 3,5-Dichloro-2-piperidinomethyl benzophenone (CAS 898773-73-4)
- N-methoxy-N-methyl-3-((triethylsilyl)oxy)propanamide (CAS 1622322-56-8)
- 3-(Bromomethyl)-5-chloro-1H-indole (CAS 1823328-51-3)
- 6-Fluoro-1-methoxy-7-methylisoquinoline (CAS 1202006-85-6)
- Droprenilamine (CAS 57653-27-7)
- 2-(((1-Ethyl-1H-benzo[d]imidazol-2-yl)methyl)thio)benzo[d]thiazole (CAS 347341-76-8)
- 1-(2,5-Dimethyl-4,5-dihydrooxazol-5-yl)ethanone (CAS 77219-13-7)
- N-Ethylpentylone HCl (CAS 17763-02-9)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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