5-Amino-2-(trifluoromethyl)pyridine-3-carboxylic acid CAS 1245913-77-2
| CAS No. | 1245913-77-2 |
| Molecular Formula | C7H5F3N2O2 |
| Molecular Weight | 206.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-2-(trifluoromethyl)pyridine-3-carboxylic acid (C7H5F3N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
5-Amino-2-(trifluoromethyl)pyridine-3-carboxylic acid (CAS 1245913-77-2) is a high-purity analytical reference standard with the molecular formula C7H5F3N2O2 and a molecular weight of 206.12 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Amino-2-(trifluoromethyl)pyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5F3N2O2 |
| Molecular Weight | 206.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-2-(trifluoromethyl)nicotinic acid (CAS 1018678-42-6)
- 4-Amino-6-(trifluoromethyl)pyridine-2-carboxylic Acid (CAS 1060810-73-2)
- 2-Amino-6-(trifluoromethyl)isonicotinic acid (CAS 1060810-74-3)
- 6-Amino-2-(trifluoromethyl)nicotinic acid (CAS 1060810-75-4)
- 2-Amino-5-nitrobenzotrifluoride (CAS 121-01-7)
- 3-Amino-5-(trifluoromethyl)picolinic acid (CAS 1214370-77-0)
- 2-Amino-4-(trifluoromethyl)nicotinic acid (CAS 1227489-68-0)
- 2-Amino-5-(trifluoromethyl)isonicotinic acid (CAS 1227582-08-2)
Recommended Standards
- 5-Hydroxy-2-(trifluoromethyl)benzoic acid (CAS 1243373-31-0)
- Desacetyl Triflusal-13C6 (CAS 1246817-12-8)
- 3-Amino-2-(trifluoromethyl)isonicotinic acid (CAS 1227598-54-0)
- 1-(2-Bromoethyl)-3-methylpiperidine (CAS 1248747-21-8)
- Cyclohexyl 3-(2-fluorophenyl)-3-(phenylsulfonyl)propanoate (CAS 2376300-31-9)
- 4-[5-(difluoromethyl)-1,2,4-oxadiazol-3-yl]aniline hydrochloride (CAS 1798731-87-9)
- 4,5-Diethyloxazol-2-amine (CAS 439145-77-4)
- (S)-2-amino-2-(5-bromo-2-fluorophenyl)ethan-1-ol hydrochloride (CAS 1391572-97-6)
- Rifamycin (CAS 6998-60-3)
- methyl 1-(2,5-dimethylphenyl)-2-mercapto-7-methyl-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-5-carboxylate (CAS 1011360-05-6)
- 2-Methyl-2H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 1394023-53-0)
- Scandium(III) carbonate hydrate (CAS 17926-77-1)
- B-Hydroxyfentanyl hydrochloride (CAS 1473-95-6)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com