Carvedilol impurity 7 CAS 1246819-01-1
| CAS No. | 1246819-01-1 |
| Molecular Formula | C27H32N2O4 |
| Molecular Weight | 448.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 448.55 g/mol gives Carvedilol impurity 7 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Carvedilol impurity 7 (CAS 1246819-01-1) is a certified pharmaceutical impurity reference standard with the molecular formula C27H32N2O4 and a molecular weight of 448.55 g/mol.
Structurally, Carvedilol impurity 7 (C27H32N2O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 448.55 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carvedilol impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H32N2O4 |
| Molecular Weight | 448.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Carvedilol Standards
- Carvedilol Impurity 33 D5 (CAS CATO-C4X-157433)
- Carvedilol Impurity 26 (CAS 2248746-67-8)
- Carvedilol Impurity 28 (CAS CATO-C4X-157428)
- Carvedilol impurity 13 (CAS CATO-C4X-157413)
- Carvedilol impurity 21 (CAS 1261395-96-3)
- Carvedilol impurity 10 (CAS 1276477-91-8)
- Carvedilol impurity 22 (CAS 142227-49-4)
- Carvedilol Impurity 27 (CAS 1059573-38-4)
Recommended Standards
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- 2-((2-Hydroxyethyl)disulfanyl)ethyl(2-butyl-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-6-yl)carba (CAS 1353569-60-4)
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- 6-Methyl-2-(3-propoxyphenyl)quinoline-4-carboxylic acid (CAS 438220-64-5)
- N-(3-(2-(dimethylamino)-5-(trifluoromethyl)pyridin-3-yl)phenyl)acetamide (CAS 1299607-76-3)
- Methyl 2-phenethyl-6-(phosphonooxy)benzoate (CAS 1171921-37-1)
- 2,2,3,3-Tetramethylcyclopropanecarbonyl Chloride (CAS 24303-61-5)
- 5-Nitro-2,3-bis(trifluoromethyl)pyridine (CAS 1806575-93-8)
- 3-[(1,2,3,4-tetrahydronaphthalen-1-yl)amino]propan-1-ol (CAS 1042574-94-6)
- ((Cys31,Nva34)-Neuropeptide Y (27-36))2 (CAS 172997-92-1)
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