Carvedilol impurity 22 CAS 142227-49-4
| CAS No. | 142227-49-4 |
| Molecular Formula | C24H26N2O5 |
| Molecular Weight | 422.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Carvedilol impurity 22 (CAS 142227-49-4) is a certified pharmaceutical impurity reference standard with the molecular formula C24H26N2O5 and a molecular weight of 422.47 g/mol.
The molecular framework of Carvedilol impurity 22 (C24H26N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Carvedilol impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H26N2O5 |
| Molecular Weight | 422.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Carvedilol Standards
- Carvedilol Impurity 27 (CAS 1059573-38-4)
- Carvedilol impurity 10 (CAS 1276477-91-8)
- Carvedilol impurity 14 (CAS 72956-35-5)
- Carvedilol impurity 21 (CAS 1261395-96-3)
- Carvedilol impurity 23 (CAS 929106-58-1)
- (±)-Carvedilol-d4 (CAS 1133705-56-2)
- Carvedilol-D4 (CAS CATO-C4X-157431)
- Carvedilol impurity 13 (CAS CATO-C4X-157413)
Recommended Standards
- 31078-10-1 (1S-(1alpha,6alpha,7beta,7aalpha))-6-Acetoxy-6,7a-dihydro-4-((isovaleryloxy)methyl)spiro(cyclopenta(c)pyran-7(1H),2'-oxiran)-1-yl isovalerate EINECS 250-454-0 Isovaltrate Isovaltratum (CAS 31078-10-1)
- 304642-94-2 Kaur-16-en-15-one,18-(acetyloxy)-7,20-epoxy-1,6,7,14-tetrahydroxy-, (1b,4a,6b,7a,14R)- (CAS 304642-94-2)
- Ipragliflozin Impurity 7 (CAS CATO-C4X-18857)
- tert-butyl (2S)-2-[(2S)-2-(benzyloxycarbonylamino)-3-methoxy-3-oxo-propyl]morpholine-4-carboxylate (CAS 2641824-60-2)
- Nicardipine EP Impurity A (Dehydro Nicardipine) (CAS 59875-58-0)
- Capivasertib Impurity 24 (CAS CATO-C4X-331224)
- Trospium Impurity 4 (Benzilide) (CAS 467-32-3)
- N-(6-Chloropyridin-3-yl)acetamide (CAS 29958-18-7)
- Octahydropyrrolo[1,2-a]pyrazin-7-ol oxalate (CAS 2306262-82-6)
- 5-Bromo-2-methyl-3-(trifluoromethyl)benzoic acid (CAS 1266728-50-0)
- (S)-2-Amino-N-(2-chloro-6-fluorobenzyl)-3-methylbutanamide (CAS 1354011-93-0)
- 2-(Pyridin-3-yl)oxazole-5-carbaldehyde (CAS 1267182-01-3)
- 6-Phenylnicotinic acid (CAS 29051-44-3)
- Neuropeptide K (human, porcine, rat) trifluoroacetate salt (CAS 96827-05-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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