Carvedilol impurity 21 CAS 1261395-96-3
| CAS No. | 1261395-96-3 |
| Molecular Formula | - |
| Molecular Weight | 427.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Carvedilol impurity 21.
Carvedilol impurity 21 (CAS 1261395-96-3) is a certified pharmaceutical impurity reference standard with the molecular formula C24H21D5N2O5 and a molecular weight of 427.50 g/mol.
Owing to deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Carvedilol impurity 21 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 427.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Carvedilol impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H21D5N2O5 |
| Molecular Weight | 427.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
Related Carvedilol Standards
- Carvedilol impurity 10 (CAS 1276477-91-8)
- Carvedilol impurity 22 (CAS 142227-49-4)
- Carvedilol Impurity 27 (CAS 1059573-38-4)
- Carvedilol impurity 13 (CAS CATO-C4X-157413)
- Carvedilol impurity 14 (CAS 72956-35-5)
- Carvedilol Impurity 26 (CAS 2248746-67-8)
- Carvedilol Impurity 28 (CAS CATO-C4X-157428)
- Carvedilol Impurity 33 D5 (CAS CATO-C4X-157433)
Recommended Standards
- Tropisetron Impurity 6 (CAS 2232112-69-3)
- Orelabrutinib (CAS 1655504-04-3)
- NVP-BAG956 (CAS 853910-02-8)
- Test Subject 0 (CAS xxx-xx-x)
- Pomalidomide Impurity 47 (CAS 885278-16-0)
- Chlorpromazine impurity 18 HCl (CAS 15502-93-9)
- Cyclobenzaprine Impurity 6 (CAS 10354-00-4)
- B-[2-(Hydroxymethyl)-4-pyridinyl]-boronic Acid (CAS 1414973-10-6)
- Azelastine Impurity 13 (CAS 791758-74-2)
- 1-(2-Methyl-4-propoxyphenyl)ethan-1-one (CAS 875818-96-5)
- N-Pht-Phe-OH (CAS 5123-55-7)
- 1-cyclobutyl-5-oxopyrrolidine-3-carbonitrile (CAS 1339014-49-1)
- N-(2-(3-(4-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)ethyl)methanesulfonamide (CAS 921552-03-6)
- Peptide Impurity 34 (CAS 21282-09-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com