Bosutinib Impurity 12 CAS 1247618-34-3
| CAS No. | 1247618-34-3 |
| Molecular Formula | C10H15NO3 |
| Molecular Weight | 197.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bosutinib Impurity 12.
Bosutinib Impurity 12 (CAS 1247618-34-3) is a certified pharmaceutical impurity reference standard with the molecular formula C10H15NO3 and a molecular weight of 197.23 g/mol.
The molecular framework of Bosutinib Impurity 12 (C10H15NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bosutinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H15NO3 |
| Molecular Weight | 197.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Bosutinib Standards
- Bosutinib Impurity 25 (CAS 98446-49-2)
- Bosutinib Impurity 7 (CAS 142072-71-7)
- Bosutinib Impurity 27 (CAS CATO-C4X-184727)
- Bosutinib Impurity 33 (CAS 709-09-1)
- Bosutinib Impurity 26 (CAS 67669-19-6)
- Bosutinib Impurity N1 (CAS 879644-03-8)
- Bosutinib Impurity 1 (CAS 20734-71-8)
- Bosutinib Impurity 6 (CAS 1156068-41-5)
Recommended Standards
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- 8-Methoxy-1-methylquinolin-4(1H)-one (CAS 127285-62-5)
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- 4-Hydroxyquinoline-7-carboxylic acid (CAS 1150618-22-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com