Bosutinib Impurity 33 CAS 709-09-1
| CAS No. | 709-09-1 |
| Molecular Formula | C8H9NO4 |
| Molecular Weight | 183.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Bosutinib Impurity 33 (CAS 709-09-1, C8H9NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Bosutinib Impurity 33 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bosutinib Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9NO4 |
| Molecular Weight | 183.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Bosutinib Standards
- Bosutinib Impurity 25 (CAS 98446-49-2)
- Bosutinib Impurity 1 (CAS 20734-71-8)
- Bosutinib Impurity 12 (CAS 1247618-34-3)
- Bosutinib Impurity 7 (CAS 142072-71-7)
- Bosutinib Impurity 27 (CAS CATO-C4X-184727)
- Bosutinib Impurity 34 (CAS 621-42-1)
- Bosutinib Impurity 26 (CAS 67669-19-6)
- Bosutinib Impurity N9 (CAS 31468-19-6)
Recommended Standards
- Entacapone impurity 38 (CAS CATO-C4X-162938)
- Pyridoxine /Vitamin B6 Impurity 67 (CAS CATO-C4X-187767)
- Allopurinol EP Impurity E (CAS 31055-19-3)
- Pyridoxine impurity 93 (CAS 524-07-2)
- Cefcapene Impurity 88 (CAS CATO-C4X-182488)
- Pentoxifylline Impurity N3 (CAS 70486-28-1)
- Ilaprazole Impurity 224 (CAS CATO-C4X-1130224)
- 9-(b-D-Arabinofuranosyl)guanine (CAS 38819-10-2)
- 1,4-Bis((3,7-dimethyloctyl)oxy)benzene (CAS 224317-93-5)
- 1-(4-(8-Amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 1589527-65-0)
- 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole (CAS 1107627-02-0)
- Dapoxetine Impurity 99 (CAS CATO-C4X-143999)
- 1-(Vinylsulfonyl)butane (CAS 16841-53-5)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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