Cabozantinib Impurity 4 CAS 1247859-37-5
| CAS No. | 1247859-37-5 |
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cabozantinib Impurity 4 (C11H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 223.20 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Cabozantinib Impurity 4 (CAS 1247859-37-5), a certified reference material (molecular formula C11H10FNO3, MW 223.20 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Cabozantinib Impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10FNO3 |
| Molecular Weight | 223.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cabozantinib Standards
- Cabozantinib Impurity 33 (CAS 849217-48-7)
- Cabozantinib Impurity 19 (CAS 18719-42-1)
- Cabozantinib Impurity 39 (CAS CATO-C4X-201839)
- Cabozantinib Impurity 41 (CAS 2105956-20-3)
- Cabozantinib Impurity 30 (CAS 261783-72-6)
- Cabozantinib Impurity 24 (CAS CATO-C4X-201824)
- Cabozantinib Impurity 27 (CAS 332-07-0)
- Cabozantinib Impurity 28 (CAS 326-04-5)
Recommended Standards
- 1-(3-(2,2,2-Trifluoroethoxy)propyl)-1h-pyrazol-3-amine (CAS 1247114-07-3)
- 2-Fluoro-4-(3-oxomorpholino)benzaldehyde (CAS 1260674-82-5)
- 3-(DIfluoromethoxy)benzene-1-sulfonamide (CAS 1228461-82-2)
- 2,6-Difluoro-4-methoxybenzene-1-sulfonamide (CAS 1261738-62-8)
- 3-(3,4-Dimethylphenyl)-1h-pyrazole-5-carbohydrazide (CAS 1028417-28-8)
- 4-(1h-Imidazol-1-yl)-2-(methylamino)butanamide (CAS 1343504-11-9)
- 1-Methyl-2,4-bis(trifluoromethyl)benzene (CAS 136664-96-5)
- 2-((2-Fluorobenzyl)oxy)-5-methylbenzaldehyde (CAS 1275969-73-7)
- Dodecanedioic acid-1,12-<SUP>13</SUP>C<SUB>2</SUB> (CAS 128017-64-1)
- tert-Butyl trans-4-(4-methylpiperazin-1-yl)cyclohexylcarbamate (CAS 1119283-74-7)
- 4-((2,6-Dichlorobenzyl)oxy)-5-methyl-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 318949-56-3)
- 2-Bromo-N-(4-butoxyphenyl)acetamide (CAS 195393-56-7)
- Felodipine Impurity 1 (CAS 68064-69-7)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com