Famotidine Impurity 28 CAS 124822-89-5
| CAS No. | 124822-89-5 |
| Molecular Formula | C6H10N6S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Famotidine Impurity 28 (CAS 124822-89-5, C6H10N6S2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Famotidine Impurity 28 (C6H10N6S2HCl) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Famotidine Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H10N6S2 2*HCl |
| Molecular Weight | 266.77 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Famotidine Standards
- Famotidine impurity HCl, >98% (CAS 100599-91-5)
- Famotidine EP Impurity I (CAS 1020719-36-1)
- Famotidine EP Impurity C (CAS 106433-44-7)
- Famotidine Impurity 23 (CAS 106649-95-0)
- Famotidine EP Impurity H (CAS 106649-96-1)
- Famotidine EP Impurity F (CAS 107880-74-0)
- Famotidine EP Impurity B Dimaleate (CAS 109467-08-5)
- Famotidine impurity 01 (CAS 1185040-73-6)
Recommended Standards
- Vilanterol Impurity 13 (CAS CATO-C4X-193513)
- Tulathromycin A Impurity 8 (CAS 2051579-09-8)
- N-Nitroso Thiamazole EP Impurity A (CAS 111348-65-3)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one (CAS 915402-06-1)
- (R)-1,2-Diphenylethanamine hydrochloride (CAS 14149-01-0)
- 2-(2-(2-Bromobenzyl)thiazol-4-yl)acetic acid (CAS 1053656-88-4)
- H-Ala-Ala-Ala-Ala-Ala-OH (CAS 10183-34-3)
- Cinitapride Impurity 12 (CAS CATO-C4X-290812)
- 1000574-50-4 7-[2-(4-Chlorophenoxy)ethylamino]-2-(methylthio)thiazolo[4,5-d]pyrimidine MFCD09877825 (CAS 1000574-50-4)
- Des-Ala18-Tirzepatide (CAS CATO-CPTD788955)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com