5-(Trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 1251923-72-4
| CAS No. | 1251923-72-4 |
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (C6H8F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1251923-72-4), molecular formula C6H8F3NO2 and molecular weight 183.13 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 4-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid (CAS 123324-24-3)
- 5-(Trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1258639-38-1)
- 5-(trifluoromethyl)-1H-pyrrole-2-carboxylic acid (CAS 1314400-72-0)
- (R)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1334160-79-0)
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Recommended Standards
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