2-Methyl-6-(trifluoromethyl)morpholin-3-one CAS 1375473-00-9
| CAS No. | 1375473-00-9 |
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Methyl-6-(trifluoromethyl)morpholin-3-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 183.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-Methyl-6-(trifluoromethyl)morpholin-3-one (CAS 1375473-00-9), a certified reference material (molecular formula C6H8F3NO2, MW 183.13 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Methyl-6-(trifluoromethyl)morpholin-3-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 4-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid (CAS 123324-24-3)
- 5-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1251923-72-4)
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- 5-(trifluoromethyl)-1H-pyrrole-2-carboxylic acid (CAS 1314400-72-0)
- (R)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1334160-79-0)
- (S)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1334160-80-3)
- 2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1481313-89-6)
- 4-(trifluoromethyl)-1h-pyrrole-2-carboxylic acid (CAS 149427-58-7)
Recommended Standards
- 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylic acid (CAS 1339115-53-5)
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- (2R,3S)-3-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1421601-22-0)
- (2s,3r)-2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1486470-94-3)
- Methyl (1,3-benzodioxol-5-yloxy)acetate (CAS 184041-88-1)
- Dy(TMHD)3 (CAS 15522-69-7)
- 3-Bromo-2-fluoro-4-(trifluoromethyl)aniline (CAS 1807176-65-3)
- 4-Quinazolone-2-carboxylic Acid (CAS 29113-34-6)
- 2-[(1S,3s)-3-acetyl-2,2-dimethyl-cyclobutyl]acetonitrile (CAS 28353-00-6)
- 2-(3-Aminotetrahydro-2h-pyran-3-yl)acetic acid (CAS 1342792-02-2)
- 2-chloranyl-1-isothiocyanato-4-nitro-benzene 2-chloro-1-isothiocyanato-4-nitrobenzene 23165-64-2 A816608 (CAS 23165-64-2)
- 7-(Methoxymethyl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine (CAS 1422136-08-0)
- 2,5-dimethyloxolan-3-one (CAS 64026-45-5)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
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