(S)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 1334160-80-3
| CAS No. | 1334160-80-3 |
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1334160-80-3), molecular formula C6H8F3NO2 and molecular weight 183.13 g/mol, is a CATO reference standard with documented purity and traceability.
(S)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (C6H8F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H8F3NO2 |
| Molecular Weight | 183.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 4-(trifluoromethyl)-1H-pyrrole-3-carboxylic acid (CAS 123324-24-3)
- 5-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1251923-72-4)
- 5-(Trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1258639-38-1)
- 5-(trifluoromethyl)-1H-pyrrole-2-carboxylic acid (CAS 1314400-72-0)
- (R)-3-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1334160-79-0)
- 2-Methyl-6-(trifluoromethyl)morpholin-3-one (CAS 1375473-00-9)
- 2-(Trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1481313-89-6)
- 4-(trifluoromethyl)-1h-pyrrole-2-carboxylic acid (CAS 149427-58-7)
Recommended Standards
- 1-(2,2,2-trifluoroethyl)azetidine-3-carboxylic acid (CAS 1339115-53-5)
- 2-((1s,2s,3s)-2-Amino-3-(trifluoromethyl)cyclopropyl)acetic acid (CAS 1305711-14-1)
- (Z)-Ethyl 3-amino-4,4,4-trifluorobut-2-enoate (CAS 141860-78-8)
- (E)-4-Amino-4-ethoxy-1,1,1-trifluoro-3-buten-2-one (CAS 128648-60-2)
- (diphenylphosphoryl)methanesulfonamide (CAS 2455521-73-8)
- 1-(3,5-Dimethylphenyl)-1H-imidazole (CAS 223762-69-4)
- Sodium Isonicotinate (CAS 16887-79-9)
- LysoPE(18:2/0:0) (CAS 85046-18-0)
- 2,6-Bis(trifluoromethyl)benzoyl chloride (CAS 53130-44-2)
- 3-Benzyloxy-4-bromo-2,6-difluorophenylboronic acid (CAS 1451393-14-8)
- Avibactam Impurity 72 (CAS CATO-C4X-134872)
- 1-(4-Amino-3,5-difluoro-2-methoxyphenyl)ethanone (CAS 1260913-54-9)
- 7-Bromo-5-chloro-2,3-dihydro-1h-indole-2,3-dione (CAS 312590-29-7)
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