Sitagliptin Impurity 73 CAS 1253056-18-6
| CAS No. | 1253056-18-6 |
| Molecular Formula | C16H12F6N4O |
| Molecular Weight | 390.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sitagliptin Impurity 73 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Sitagliptin Impurity 73 (CAS 1253056-18-6) is a certified pharmaceutical impurity reference standard with the molecular formula C16H12F6N4O and a molecular weight of 390.28 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Sitagliptin Impurity 73 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 390.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H12F6N4O |
| Molecular Weight | 390.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sitagliptin Standards
- Sitagliptin Impurity 57 (CAS 1803026-58-5)
- Sitagliptin Impurity 96 (CAS 1675201-14-5)
- Sitagliptin Impurity 86 (CAS 1246961-45-4)
- Sitagliptin Impurity 75 (CAS 1334244-24-4)
- Sitagliptin Impurity 151 (CAS 1334244-32-4)
- Sitagliptin Impurity 152 (CAS CATO-C4X-1144152)
- Sitagliptin EP Impurity C (CAS 945261-48-3)
- Sitagliptin EP Impurity B (CAS 486460-31-5)
Recommended Standards
- Canagliflozin impurity 9 (CAS 2444540-01-4)
- Diisooctyl phthalate (CAS 27554-26-3)
- tert-Butyl 3,8-dimethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine-1-carboxylate (CAS 2770331-83-2)
- 1-(4-Fluorophenyl)-9-methyl-2-(2,3,4-trifluorophenoxy)-1H-purin-6(9H)-one (CAS 1009032-45-4)
- Parecoxib Impurity 25 (CAS 1884279-18-8)
- Letermovir Impurity 18 (CAS CATO-C4X-291518)
- Olanzapine Impurity 64 (CAS CATO-C4X-117864)
- 2,3-dihydrospiro[indene-1,3'-pyrrolidine]-2',5'-dione (CAS 81402-16-6)
- 7-Bromo-6-chloro-5,8-difluoroquinazolin-4(3H)-one (CAS 2387928-71-2)
- (S)-5-(((Trimethylsilyl)oxy)methyl)pyrrolidin-2-one (CAS 170885-02-6)
- 12-Hydroxyisobakuchiol (CAS 178765-55-4)
- methyl 2-[2-(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethoxy)ethoxy]acetate (CAS 1820619-06-4)
- 2-Methyl-5-(p-tolyl)furan-3-carboxylic acid (CAS 111787-86-1)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com