Sitagliptin Impurity 86 CAS 1246961-45-4
| CAS No. | 1246961-45-4 |
| Molecular Formula | C19H26F3NO4 |
| Molecular Weight | 389.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sitagliptin Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Sitagliptin Impurity 86 (CAS 1246961-45-4), a pharmacopoeial impurity reference standard (molecular formula C19H26F3NO4, MW 389.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H26F3NO4, Sitagliptin Impurity 86 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 389.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H26F3NO4 |
| Molecular Weight | 389.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Sitagliptin Standards
- Sitagliptin Impurity 75 (CAS 1334244-24-4)
- Sitagliptin Impurity 151 (CAS 1334244-32-4)
- Sitagliptin Impurity 152 (CAS CATO-C4X-1144152)
- Sitagliptin EP Impurity C (CAS 945261-48-3)
- Sitagliptin EP Impurity B (CAS 486460-31-5)
- Sitagliptin Impurity 99 (CAS 486459-88-5)
- Sitagliptin Impurity 57 (CAS 1803026-58-5)
- Sitagliptin Impurity 73 (CAS 1253056-18-6)
Recommended Standards
- Linagliptin impurity 152 (CAS CATO-C4X-1101152)
- Nafamostat impurity 110 (CAS 107490-62-0)
- Ibrutinib Impurity 174 (CAS CATO-C4X-1064174)
- Pantoprazole-d6 (CAS 922727-65-9)
- Etomidate Impurity 42 (CAS CATO-C4X-188442)
- Bilastine Impurity 138 (CAS CATO-C4X-2253138)
- (E)-Ceftazidime Impurity 37 (CAS CATO-C4X-121237)
- 4-(azetidin-1-yl)-6-chloro-2-cyclopropylpyrimidine (CAS 617718-49-7)
- Bufotalidin (CAS 465-90-7)
- (3R,5S)-5-(hydroxymethyl)-1-tosylpyrrolidin-3-ol (CAS 5605-46-9)
- Methyl 2-(4-hydroxypiperidin-1-yl)-6-methylpyrimidine-4-carboxylate (CAS 1355194-49-8)
- 2-Amino-n-[3-(pyrrolidin-1-yl)phenyl]pentanamide (CAS 1218021-92-1)
- 2-iodo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine (CAS CATO-C3D-262290)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com