Landiolol Impurity N8 HCl CAS 1253907-85-5
| CAS No. | 1253907-85-5 |
| Molecular Formula | C25H39N3O8 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 546.06 g/mol gives Landiolol Impurity N8 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Landiolol Impurity N8 HCl (CAS 1253907-85-5), a pharmacopoeial impurity reference standard (molecular formula C25H39N3O8HCl, MW 546.06 g/mol) used for the identification and quantification of trace impurities in APIs.
Landiolol Impurity N8 HCl (C25H39N3O8HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Landiolol Impurity N8 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H39N3O8 HCl |
| Molecular Weight | 546.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Landiolol Standards
- Landiolol Impurity 44 (CAS 115314-14-2)
- Landiolol Impurity 2 (CAS 115314-17-5)
- Landiolol Impurity N11 HCl (CAS 1253907-81-1)
- Landiolol Impurity N10 HCl (CAS 1253907-83-3)
- Landiolol Impurity 4 (CAS 133242-29-2)
- Landiolol Impurity 1 (CAS 144256-11-1)
- Landiolol Impurity 15 (CAS 144256-12-2)
- Landiolol Impurity 13 (CAS 144256-25-7)
Recommended Standards
- Alectinib Impurity 67 (CAS CATO-C4X-283667)
- Urapidil Impurity 65 (CAS 2468009-96-1)
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- Methyl 4-bromo-7-methoxyquinoline-6-carboxylate (CAS 2089310-53-0)
- 2-(4-Chlorophenyl)-4-(pyrrolidine-1-carbonyl)phthalazin-1(2H)-one (CAS 320417-92-3)
- (R)-1,2,3,4-Tetrahydroquinolin-3-amine dihydrochloride (CAS 145554-64-9)
- (3-Bromobenzoyl)pyrrolidine (CAS 346721-91-3)
- 2-(1-methyl-1H-indol-3-yl)ethan-1-amine hydrochloride (CAS 2826-96-2)
- Z-Arg-Arg-AMC (CAS 88937-61-5（free base）)
- [Nva12]-Tirzepatide (CAS CATO-C4X-324042)
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