Alectinib Impurity 67 CAS CATO-C4X-283667
| CAS No. | CATO-C4X-283667 |
| Molecular Formula | C13H17IO |
| Molecular Weight | 316.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H17IO, Alectinib Impurity 67 contains a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Alectinib Impurity 67 (CAS CATO-C4X-283667) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17IO and a molecular weight of 316.18 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17IO |
| Molecular Weight | 316.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Alectinib Standards
- Alectinib impurity 01 (CAS 1256584-82-3)
- Alectinib Impurity 3 (CAS 1256584-73-2)
- Alectinib Impurity 91 (CAS CATO-C4X-283691)
- Alectinib impurity 27 (CAS CATO-C4X-283627)
- Alectinib Impurity 58 (CAS CATO-C4X-283658)
- Alectinib Impurity 48 (CAS CATO-C4X-283648)
- Alectinib Impurity 1 (CAS 1256578-99-0)
- Alectinib Impurity 65 (CAS CATO-C4X-283665)
Recommended Standards
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