Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate CAS 1255666-33-1
| CAS No. | 1255666-33-1 |
| Molecular Formula | C13H15F2NO3 |
| Molecular Weight | 271.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 271.26 g/mol gives Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate (CAS 1255666-33-1), a certified reference material (molecular formula C13H15F2NO3, MW 271.26 g/mol) for analytical method development and quality control.
Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate (C13H15F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H15F2NO3 |
| Molecular Weight | 271.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- Benzyl 4,4-difluoro-3-hydroxypiperidine-1-carboxylate (CAS 1334417-91-2)
- Benzyl 3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 174073-95-1)
- N'-(4,6-Difluoro-1,3-benzothiazol-2-yl)-N,N-dimethylpropane-1,3-diamine (CAS 1105188-28-0)
- 2,2-difluoro-1,3-benzodioxole-4-carbonyl bromide (CAS 668275-94-3)
- (2,2-Difluoro-7,10-dioxadispiro[2.2.4(6).2(3)]Dodecan-1-yl)trifluoroborate (CAS 2416056-43-2)
- (2,3-Difluoro-4-(heptyloxy)phenyl)boronic acid (CAS 147222-88-6)
- 2-(3,3-difluoro-5-nitro-2-oxo-2,3-dihydro-1H-indol-1-yl)acetic acid (CAS 1864014-62-9)
- 951888-57-6 3,4-Difluoro-3',4',5'-trifluorobenzophenone MFCD09801716 (CAS 951888-57-6)
Recommended Standards
- 1-(2,4-Difluorophenyl)-4-phenyl-1H-pyrazol-5-amine (CAS 1202029-37-5)
- 6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine (CAS 1262888-28-7)
- Nifuratel Impurity 5 (CAS 34143-33-4)
- Methyl 5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylate (CAS 932243-23-7)
- N,N'-((1,4-phenylenebis(oxy))bis(ethane-2,1-diyl))diacetamide (CAS 893768-96-2)
- N-Nitroso-Tamsulosin d4 Impurity (Mixture of isomers) (CAS CATO-C4X-118776)
- 7,9-Dichloro-1,2,3,4-tetrahydroacridine (CAS 53618-66-9)
- 4-Chloro-6,7-dimethoxy-2-methylquinazoline (CAS 50377-49-6)
- 4-(3-Bromophenyl)pyrimidin-2-amine (CAS 392307-25-4)
- (S)-2-((S)-2-Amino-N-(4-methyl-2-oxo-2H-chromen-6-yl)propanamido)-5-guanidinopentanamide xhydrochloride (CAS 83363-71-7)
- 2-Methoxyethyl 1,4-dihydro-5-methyl-4-oxo-2-(3-pyridinyl)thieno[2,3-d]pyrimidine-6-carboxylate (CAS 727982-66-3)
- Allopurinol Impurity 9 (CAS 41621-10-7)
- 4-Hydroxy-5-isopropyl-2-methylcyclohex-2-en-1-one (CAS 61570-82-9)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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