Nifuratel Impurity 5 CAS 34143-33-4
| CAS No. | 34143-33-4 |
| Molecular Formula | C9H9N3O5S |
| Molecular Weight | 271.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Nifuratel Impurity 5 (C9H9N3O5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Nifuratel Impurity 5 (CAS 34143-33-4, C9H9N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9N3O5S |
| Molecular Weight | 271.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Nifuratel Standards
- Nifuratel Impurity 3 (CAS CATO-C4X-12723)
- Nifuratel Impurity 34 (CAS CATO-C4X-127234)
- Nifuratel (CAS 4936-47-4)
- Nifuratel Impurity 20 (CAS CATO-C4X-127220)
- Nifuratel Impurity 23 (CAS CATO-C4X-127223)
- Nifuratel Impurity 35 (CAS CATO-C4X-127235)
- Nifuratel Impurity 6 (CAS 41359-15-3)
- Nifuratel Impurity 18 (CAS CATO-C4X-127218)
Recommended Standards
- Methyl 5-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylate (CAS 932243-23-7)
- 1-(2,4-Difluorophenyl)-4-phenyl-1H-pyrazol-5-amine (CAS 1202029-37-5)
- 8-(3-Fluorophenoxy)imidazo[1,2-a]pyrazine-6-carboximidamide (CAS 2052362-58-8)
- Benzyl 3,3-difluoro-4-hydroxypiperidine-1-carboxylate (CAS 1255666-33-1)
- Mirogabalin Impurity 15 (CAS CATO-C4X-292415)
- Teneligliptin Impurity 54 (CAS CATO-C4X-176054)
- Verapamil EP Impurity C (CAS 3490-05-9)
- 6-(Trifluoromethyl)chroman-3-carboxylic Acid (CAS 944899-33-6)
- Tert-butyl 4-(pyrrolidine-1-carbonyl)piperidine-1-carboxylate (CAS 188979-06-8)
- Diphenoxylate Impurity 4 (CAS 84255-02-7)
- (4-Bromo-2-fluoro-5-methyl-phenyl)-carbamic acid tert-butyl ester (CAS 1260804-94-1)
- (4-Chloro-2-(piperidin-3-yl)phenyl)boronic acid (CAS 2225151-96-0)
- Leuprorelin EP Impurity K Acetate (CAS CATO-C4X-182212)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
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