6-Chloro-5-fluoropyridin-2-amine CAS 1256808-75-9
| CAS No. | 1256808-75-9 |
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 6-Chloro-5-fluoropyridin-2-amine (CAS 1256808-75-9), a certified reference material (molecular formula C5H4ClFN2, MW 146.55 g/mol) for analytical method development and quality control.
Owing to a nitrile group, fluorine/chlorine substitution, 6-Chloro-5-fluoropyridin-2-amine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 146.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4ClFN2 |
| Molecular Weight | 146.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-2-fluoropyridin-3-amine (CAS 103999-78-6)
- 4-Chloro-6-(fluoromethyl)pyrimidine (CAS 1092289-36-5)
- 5-Chloro-2-fluoropyridin-4-amine (CAS 1227513-74-7)
- 3-Chloro-2-fluoropyridin-4-amine (CAS 1227577-11-8)
- 3-Chloro-5-fluoropyridin-4-amine (CAS 1227581-38-5)
- 6-Chloro-2-fluoropyridin-3-amine (CAS 1227600-05-6)
- 3-chloro-6-fluoropyridin-2-amine (CAS 1232431-23-0)
- 5-Chloro-6-fluoropyridin-3-amine (CAS 1256790-26-7)
Recommended Standards
- 4-Chloro-6-fluoropyridin-3-amine (CAS 1256808-96-4)
- 5-Amino-2-chloro-4-fluoropyridine (CAS 1256811-74-1)
- 5-Chloro-4-fluoropyridin-3-amine (CAS 1256834-58-8)
- 6-chloro-3-fluoro-pyridin-2-amine (CAS 1260672-14-7)
- N-[3-(1H-imidazol-1-yl)propyl]-4,6-dimethyl-1,3-benzothiazol-2-amine (CAS 1204297-87-9)
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