Rivaroxaban Impurity 55 CAS 1257527-98-2
| CAS No. | 1257527-98-2 |
| Molecular Formula | C21H21N3O5 |
| Molecular Weight | 395.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Rivaroxaban Impurity 55 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Rivaroxaban Impurity 55 (CAS 1257527-98-2), a pharmacopoeial impurity reference standard (molecular formula C21H21N3O5, MW 395.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H21N3O5, Rivaroxaban Impurity 55 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 395.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O5 |
| Molecular Weight | 395.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
Related Rivaroxaban Standards
- Rivaroxaban impurity 176 (CAS CATO-C4X-1090176)
- Rivaroxaban impurity 196 (CAS CATO-C4X-1090196)
- Rivaroxaban Impurity 39 (CAS 446292-07-5)
- Rivaroxaban Impurity 43 (CAS 1369969-44-7)
- Rivaroxaban Desmorpholinone Analog (CAS 936232-22-3)
- Rivaroxaban Impurity 123 (CAS CATO-C4X-1090123)
- Rivaroxaban Impurity 163 (CAS 2422046-61-3)
- Rivaroxaban Impurity 78 (CAS CATO-C4X-109078)
Recommended Standards
- Ceftriaxone Sodium EP Impurity B(Cefotaxime EP Impurity E)（Cefodizime Impurity D） (CAS 66340-33-8)
- Cefotaxime Impurity 22 (CAS CATO-C4X-120122)
- Cefdinir (CAS 91832-40-5)
- Cefdinir CP Impurity R (CAS 178601-88-2)
- Valsartan Impurity 104 (CAS CATO-C4X-1057104)
- Lusutrombopag Impurity 76 (CAS CATO-C4X-208476)
- Erdafitinib Impurity 7 (CAS CATO-C4X-26167)
- 5-(tert-Butyl)quinolin-8-ol (CAS 126403-66-5)
- 3-[(4-Methoxyphenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338405-85-9)
- 3-Chloro-1H-indole-6-carboxylic acid (CAS 219508-17-5)
- Chloroprocaine (CAS 133-16-4)
- 5-tert-Butyl 1-ethyl 5-azaspiro[2.5]octane-1,5-dicarboxylate (CAS 1590372-41-0)
- (R)-tert-Butyl (1-fluoro-3-phenylpropan-2-yl)carbamate (CAS 2761225-71-0)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com