Cefotaxime Impurity 22 CAS CATO-C4X-120122
| CAS No. | CATO-C4X-120122 |
| Molecular Formula | C14H13N5O5S2 |
| Molecular Weight | 395.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefotaxime Impurity 22 (CAS CATO-C4X-120122, C14H13N5O5S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefotaxime Impurity 22 (C14H13N5O5S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H13N5O5S2 |
| Molecular Weight | 395.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Cefotaxime Standards
- Cefotaxime EP Impurity A (CAS 65052-63-3)
- Cefotaxime Impurity 45 (CAS 1950566-51-4)
- Cefotaxime Impurity 33 (CAS CATO-C4X-120133)
- Cefotaxime Impurity 52 (CAS 57254-16-7)
- Cefotaxime Impurity 50 (CAS CATO-C4X-120150)
- Cefotaxime Impurity 50 (CAS CATO-C4X-120157)
- Cefotaxime Impurity 95 (CAS CATO-C4X-120195)
- Cefotaxime EP Impurity B (CAS 66340-28-1)
Recommended Standards
- Ceftriaxone Sodium EP Impurity B(Cefotaxime EP Impurity E)（Cefodizime Impurity D） (CAS 66340-33-8)
- Cefdinir (CAS 91832-40-5)
- Rivaroxaban Impurity 55 (CAS 1257527-98-2)
- Cefdinir CP Impurity R (CAS 178601-88-2)
- Relebactam Impurity 19 (CAS CATO-C4X-214419)
- Crisaborole Impurity 66 (CAS 2247957-30-6)
- Lansoprazole impurity 73 (CAS CATO-C4X-111373)
- 2-Bromomethyl-1-methoxy-3-nitro-benzene (CAS 19689-86-2)
- 3-Chlorobenzo[4,5]imidazo[1,2-a]pyrimidine-2-carboxylic acid (CAS 1956331-37-5)
- 2,7-Dimethyl-2-(4,8,12-trimethyltridecyl)chroman-6-ol (CAS 91-86-1)
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- trans-o-Hydroxylbenzal pyruvic disodium salt (CAS 145761-42-8)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
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