Erdafitinib Impurity 7 CAS CATO-C4X-26167
| CAS No. | CATO-C4X-26167 |
| Molecular Formula | C25H29ClN6O2 |
| Molecular Weight | 480.99 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Erdafitinib Impurity 7 (CAS CATO-C4X-26167) is a certified pharmaceutical impurity reference standard with the molecular formula C25H29ClN6O2 and a molecular weight of 480.99 g/mol.
The molecular framework of Erdafitinib Impurity 7 (C25H29ClN6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C25H29ClN6O2 |
| Molecular Weight | 480.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Erdafitinib Standards
- Erdafitinib Impurity 6 (CAS CATO-C4X-26166)
- Erdafitinib Impurity 5 (CAS CATO-C4X-26165)
- Erdafitinib (CAS 1346242-81-6)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
- Erdafitinib Impurity 9 (CAS CATO-C4X-26169)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 8 (CAS CATO-C4X-26168)
Recommended Standards
- Methyl 2-({5-[1-(4-chlorobenzenesulfonamido)-2-phenylethyl]-4-methyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetate (CAS 338794-32-4)
- Clobetasol butyrate (CAS 25122-47-8)
- A-887826 (CAS 1266212-81-0)
- Clobetasone butyrate EP Impurity E (CAS 639817-48-4)
- Oseltamivir Impurity 22 (CAS CATO-C4X-172022)
- Imatinib EP Impurity B DiHCl (CAS 581076-67-7)
- Lornoxicam Impurity 12 (CAS 2469039-23-2)
- n-Isopropyl-2-(mesityloxy)acetamide (CAS 431057-61-3)
- Naphthalene-2,7-diyl diacetate (CAS 22472-26-0)
- 2-(Chloromethyl)-3-(furan-2-ylmethyl)-3,4-dihydroquinazolin-4-one (CAS 923729-61-7)
- 4-(Benzo[d][1,3]dioxol-5-yl)thiazol-2-amine (CAS 185613-91-6)
- 4-(4-Butyl-phenyl)-5-thiophen-2-yl-4H-[1,2,4]triazole-3-thiol (CAS 525581-96-8)
- 2,4-Dichloro-6-(naphthalen-2-yl)-1,3,5-triazine (CAS 112719-97-8)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
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