6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine CAS 1258402-42-4
| CAS No. | 1258402-42-4 |
| Molecular Formula | C14H16BF3N2O2 |
| Molecular Weight | 312.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine (C14H16BF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.5, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 312.10 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1258402-42-4), molecular formula C14H16BF3N2O2 and molecular weight 312.10 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H16BF3N2O2 |
| Molecular Weight | 312.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tetramethyl Standards
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1198094-97-1)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1H-indazole (CAS 1454300-91-4)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1620574-99-3)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)-1H-indazole (CAS 1821029-13-3)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-3H-1,3-benzodiazole (CAS 2284623-82-9)
- 4,4,5,5-Tetramethyl-2-((1R,2R)-2-(4-(trifluoromethyl)phenyl)cyclopropyl)-1,3,2-dioxaborolane (CAS 1240492-30-1)
- 4,4,5,5-Tetramethyl-2-(4-(1-(trifluoromethyl)cyclopropyl)phenyl)-1,3,2-dioxaborolane (CAS 1431983-70-8)
- (E)-4,4,5,5-Tetramethyl-2-(3-(4-(trifluoromethyl)phenyl)prop-1-en-1-yl)-1,3,2-dioxaborolane (CAS 1444827-08-0)
Recommended Standards
- 1-Butoxy-2,3-difluoro-4-iodobenzene (CAS 1366126-91-1)
- 2-Bromo-1-(4-fluorophenoxy)-4-nitrobenzene (CAS 477856-83-0)
- 3-Bromo-2-methyl-5-(pentafluorothio)aniline (CAS 1373920-91-2)
- 2-(2-Bromo-4-fluorophenoxy)pyridine-3-carboxylic acid (CAS 954563-46-3)
- 1-(2-Methyl-3-(trifluoromethyl)benzyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1604037-00-4)
- Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate (CAS 1010120-59-8)
- 2-[1-(2-methylpropyl)-5-oxo-2,5-dihydro-1h-pyrazol-3-yl]acetic acid (CAS 852851-73-1)
- 3-Aminoazetidine (CAS 102065-86-1)
- Methyl 4-[(3-pyrrolidinylmethoxy)methyl]benzoatehydrochloride (CAS 1219972-28-7)
- 3,5-Difluoro-4-methoxythiophenol (CAS 1208078-01-6)
- 1-(2,3-Difluoro-6-nitrophenoxy)propan-2-one (CAS 82419-32-7)
- Galantamine EP Impurity D (Anhydro Galantamine) HCl (CAS CATO-C4X-143521)
- tert-Butyl 2-(2-Methyl-1-pyrrolidinyl)acetate (CAS 2015655-98-6)
- D-Thr7-Tirzepatide (CAS CATO-CPTD788924)
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