1-Butoxy-2,3-difluoro-4-iodobenzene CAS 1366126-91-1
| CAS No. | 1366126-91-1 |
| Molecular Formula | C10H11F2IO |
| Molecular Weight | 312.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Butoxy-2,3-difluoro-4-iodobenzene.
1-Butoxy-2,3-difluoro-4-iodobenzene (CAS 1366126-91-1) is a high-purity analytical reference standard with the molecular formula C10H11F2IO and a molecular weight of 312.10 g/mol.
The molecular framework of 1-Butoxy-2,3-difluoro-4-iodobenzene (C10H11F2IO) is characterized by a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11F2IO |
| Molecular Weight | 312.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
Related Butoxy Standards
- 9-[(tert-butoxy)carbonyl]-4-oxo-3,9-diazaspiro[5.5]undecane-1-carboxylic acid (CAS 1357353-26-4)
- 5-Butoxy-2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one (CAS 81778-82-7)
- 4-Butoxy-N-(2-hydroxy-2-methyl-3-(methylthio)propyl)benzamide (CAS 1396879-29-0)
- 2-[(tert-Butoxy)carbonyl]-hexahydro-1H-spiro[cyclopenta[c]pyrrole-5,2'-[1,3]dioxolane]-3-carboxylic acid (CAS 1638759-49-5)
- 6-(sec-Butoxy)-2-((2-chlorophenyl)thio)pyrimidin-4(3H)-one (CAS 284681-68-1)
- 6-(sec-Butoxy)-2-((3-chlorophenyl)thio)pyrimidin-4(3H)-one (CAS 284681-69-2)
- 6-(sec-Butoxy)-2-((4-chlorophenyl)thio)pyrimidin-4(3H)-one (CAS 284681-70-5)
- 3-(sec-Butoxy)-N-(3-propoxybenzyl)aniline (CAS 1040686-04-1)
Recommended Standards
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1258402-42-4)
- 3-Bromo-2-methyl-5-(pentafluorothio)aniline (CAS 1373920-91-2)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1198094-97-1)
- 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)-1H-indazole (CAS 1454300-91-4)
- 2-[(4-Amino-2-fluorophenyl)amino]ethanol (CAS 1039868-68-2)
- 2-{[(1E)-2-acetyl-2-[(1,3-thiazol-2-yl)carbamoyl]eth-1-en-1-yl]amino}acetic acid (CAS 303998-82-5)
- N-((2S,3R,4R,5S,6R)-4,5-Dihydroxy-2-((3'-hydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 148806-95-5)
- (E)-N-(3-Cyanophenyl)-N'-methyl-3-(trifluoromethyl)benzene-1-carboximidamide (CAS 339028-23-8)
- 3-Bromo-5-(naphthalen-2-ylsulfonyl)-1,2,4-thiadiazole (CAS 1000575-53-0)
- Tert-butyl ((1S,2S,3R,5S)-2,6,6-trimethyl-3-(methylcarbamoyl)bicyclo[3.1.1]Heptan-2-yl)carbamate (CAS 705949-12-8)
- 7-Azaspiro[3.5]nonane-2-carbonitrile (CAS 203662-67-3)
- 4-Amino-3-(difluoromethyl)-5-(trifluoromethyl)picolinaldehyde (CAS 1806969-20-9)
- 5-Iodo-2-methoxypyridine (CAS 13472-61-2)
- Semaglutide impurity 50 (CAS 2773558-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com