Montelukast Impurity 19 CAS 1258428-71-5
| CAS No. | 1258428-71-5 |
| Molecular Formula | C29H26ClNO2 |
| Molecular Weight | 455.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Montelukast Impurity 19 (CAS 1258428-71-5), a pharmacopoeial impurity reference standard (molecular formula C29H26ClNO2, MW 455.98 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Montelukast Impurity 19 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 455.98 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H26ClNO2 |
| Molecular Weight | 455.98 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Montelukast Standards
- Montelukast 3-Oxo Benzoate (CAS 149968-11-6)
- Montelukast Impurity 36 (CAS 142569-69-5)
- Montelukast (3R)-Hydroxy Benzoate (CAS 150026-72-5)
- Montelukast Impurity 10 (CAS 150026-75-8)
- Montelukast Impurity 31 (CAS 287930-77-2)
- Montelukast Impurity 47 (CAS 1079753-36-8)
- Montelukast Impurity 49 (CAS CATO-C4X-103149)
- Montelukast Impurity 11 (CAS 120578-04-3)
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