2-((4-Chlorophenyl)amino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid CAS 1258637-95-4
| CAS No. | 1258637-95-4 |
| Molecular Formula | C19H10ClNO4S |
| Molecular Weight | 383.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((4-Chlorophenyl)amino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid.
2-((4-Chlorophenyl)amino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid (CAS 1258637-95-4), molecular formula C19H10ClNO4S and molecular weight 383.81 g/mol, is a CATO reference standard with documented purity and traceability.
2-((4-Chlorophenyl)amino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid (C19H10ClNO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((4-Chlorophenyl)amino)-4,9-dioxo-4,9-dihydronaphtho[2,3-b]thiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H10ClNO4S |
| Molecular Weight | 383.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
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- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,4,5-trifluorophenyl)acetamide (CAS 303091-66-9)
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Recommended Standards
- 2-Amino-1-(1-aza-2-(2-(4-chlorophenylthio)-5-nitrophenyl)vinyl)ethene-1,2-dicarbonitrile (CAS 1024763-94-7)
- 2-(4-((4-Chloro-2-nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (CAS 866153-27-7)
- Cefaclor Impurity 20 (CAS CATO-C4X-127020)
- Cefaclor Oxide Impurity (CAS CATO-C4X-127022)
- 1,4-Diethynyl-2-nitrobenzene (CAS 113639-27-3)
- tert-Butyl 4,4-difluoro-5-(((trifluoromethyl)sulfonyl)oxy)pentanoate (CAS 1782101-26-1)
- 4-Chloro-6-methyl-2-phenyl-5-(3-(trifluoromethyl)phenoxy)pyrimidine (CAS 680217-69-0)
- cis-3-fluorooxan-4-amine (CAS 1631027-04-7)
- N-(tert-Butyl)-4-(methylthio)-1,3,5-triazin-2-amine (CAS 109202-19-9)
- tert-Butyl 4-(1-oxo-1,2-dihydroisoquinolin-6-yloxy)piperidine-1-carboxylate (CAS 1982780-61-9)
- 3-[(tert-Butoxy)carbonyl]bicyclo[1.1.1]pentane-1-carboxylic acid (CAS 1638765-30-6)
- (2r,3r,4r,5r)-5-({[{[{[(2r,3s,4r,5r)-5-{6-[(2-aminoethyl)amino]-9h-purin-9-yl}-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-2-(3-carbamoylpyridinium-1-yl)-4-hydroxytetrahydrofuran-3-olate(non-preferred name) 6627-78-7 KST-1A7236 (CAS 6627-78-7)
- 1-Methyl-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4(1H)-one (CAS 59105-03-2)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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