5-((4-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide CAS 338791-90-5
| CAS No. | 338791-90-5 |
| Molecular Formula | C15H8ClF2N3OS2 |
| Molecular Weight | 383.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-((4-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-((4-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide (CAS 338791-90-5) is a high-purity analytical reference standard with the molecular formula C15H8ClF2N3OS2 and a molecular weight of 383.82 g/mol.
The molecular framework of 5-((4-Chlorophenyl)thio)-N-(2,4-difluorophenyl)-1,2,3-thiadiazole-4-carboxamide (C15H8ClF2N3OS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H8ClF2N3OS2 |
| Molecular Weight | 383.82 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 2-(((6-Chloropyridin-3-yl)methyl)thio)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 889947-49-3)
- 5-(Chloromethyl)-4-(phenoxymethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 592518-75-7)
- 1-(Tert-butyl) 2-methyl (2S,4S)-4-(3-chloro-4-formylphenoxy)pyrrolidine-1,2-dicarboxylate (CAS 2442510-17-8)
- Ethyl 2-((3-acetyl-6-chloro-4-phenylquinolin-2-yl)oxy)acetate (CAS 378774-63-1)
- 4-Ethyl-5-methoxy-2-[4-(4-methoxyphenyl)-5-isoxazolyl]phenol (CAS 129414-88-6)
- N-((1H-benzo[d]imidazol-2-yl)methyl)-2-chlorobenzamide (CAS 338410-53-0)
- 2-(3,4-Dihydroxybutyl)quinoxaline (CAS 80840-08-0)
- Etoricoxib Impurity 33 (CAS 1817735-82-2)
- 4-Chloro-3-methoxy-5-nitropyridin-2-amine (CAS 1956379-48-8)
- Tert-butyl 2-(furan-2-yl)pyrrolidine-1-carboxylate (CAS 1355207-54-3)
- 5-Bromo-4-methyl-N-(p-tolyl)pyridin-2-amine (CAS 1220017-89-9)
- N-(3,3-difluorocyclobutyl)thietan-3-amine (CAS 1855843-20-7)
- (5-Bromo-3-methylpyridin-2-yl)methanamine (CAS 886365-53-3)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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