1-Amino-3-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxylic acid CAS 1258640-23-1
| CAS No. | 1258640-23-1 |
| Molecular Formula | C12H12F3NO2 |
| Molecular Weight | 259.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-Amino-3-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxylic acid (CAS 1258640-23-1), molecular formula C12H12F3NO2 and molecular weight 259.22 g/mol, is a CATO reference standard with documented purity and traceability.
1-Amino-3-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxylic acid (C12H12F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 1-Amino-3-(4-(trifluoromethyl)phenyl)cyclobutane-1-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12F3NO2 |
| Molecular Weight | 259.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 3-Cyclopropoxy-N-methyl-2-(trifluoromethyl)benzamide (CAS 1243480-64-9)
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- 3-Cyclopropoxy-N-methyl-4-(trifluoromethyl)benzamide (CAS 1243445-27-3)
- 4-Cyclopropoxy-N-methyl-2-(trifluoromethyl)benzamide (CAS 1243410-50-5)
- (7-Nitro-1H-indol-3-yl)methanol (CAS 1360963-90-1)
- Phthalimidomethyl butyl trithiocarbonate (CAS 19194-21-9)
- 1-(sec-Butyl)-N-((1,5-dimethyl-1H-pyrazol-4-yl)methyl)-1H-pyrazol-3-amine hydrochloride (CAS 1856039-34-3)
- (E)-5-Phenylpent-4-enoic acid (CAS 17920-83-1)
- 3-Chloro-4-iodobenzaldehyde (CAS 148334-14-9)
- Ganciclovir triphosphate triethylamine salt (CAS 86761-38-8)
- 2-(3-Fluorophenyl)-1-(4-fluorophenyl)ethan-1-one (CAS 370874-66-1)
- Methyl 2-chloro-5-(trifluoromethyl)isonicotinate (CAS 1246685-28-8)
- 2-chloro-N-(6-chloropyridin-3-yl)acetamide hydrochloride (CAS 1955524-57-8)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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