4-Amino-1-[(3S,4S,5R)-3-(Fluoromethyl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One CAS 152502-85-7
| CAS No. | 152502-85-7 |
| Molecular Formula | C10H14FN3O4 |
| Molecular Weight | 259.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Amino-1-[(3S,4S,5R)-3-(Fluoromethyl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 259.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-Amino-1-[(3S,4S,5R)-3-(Fluoromethyl)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One (CAS 152502-85-7), molecular formula C10H14FN3O4 and molecular weight 259.23 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14FN3O4 |
| Molecular Weight | 259.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- Methyl 4-(3-fluoropyridin-4-yl)-3-formylbenzoate (CAS 1643978-45-3)
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- 3-(1h-1,2,4-Triazol-1-yl)propanenitrile (CAS 76686-83-4)
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- 2-Methyl-5-(((2-methylthiazol-4-yl)methyl)thio)-1,3,4-thiadiazole (CAS 670273-10-6)
- (Z)-3-(4-chlorophenyl)-4,4,4-trifluorobut-2-enoic acid (CAS 1613503-49-3)
- 4,6-Dichloro-2,3-difluoroaniline (CAS 1806300-96-8)
- 2,4-Dimethoxy-N-(3-(3-methylpentan-3-yl)isoxazol-5-yl)benzamide (CAS 189038-97-9)
- Cefminox Impurity 15 (CAS CATO-C4X-192615)
- 6-Chloro-2-(4-isobutoxyphenyl)quinoline-4-carboxylic acid (CAS 932928-98-8)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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