6-(Bromomethyl)-4-chloro-7-methoxyquinoline-3-carbonitrile CAS 1259017-81-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1259017-81-6
Molecular FormulaC12H8BrClN2O
Molecular Weight311.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-(Bromomethyl)-4-chloro-7-methoxyquinoline-3-carbonitrile CAS 1259017-81-6 chemical structure

Description

CATO manufactures 6-(Bromomethyl)-4-chloro-7-methoxyquinoline-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

6-(Bromomethyl)-4-chloro-7-methoxyquinoline-3-carbonitrile (CAS 1259017-81-6) is a high-purity analytical reference standard with the molecular formula C12H8BrClN2O and a molecular weight of 311.56 g/mol.

The molecular framework of 6-(Bromomethyl)-4-chloro-7-methoxyquinoline-3-carbonitrile (C12H8BrClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC12H8BrClN2O
Molecular Weight311.56 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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