Xylometazoline Impurity 9 CAS 1260490-37-6
| CAS No. | 1260490-37-6 |
| Molecular Formula | C14H20O3 |
| Molecular Weight | 236.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Xylometazoline Impurity 9 (CAS 1260490-37-6) is a certified pharmaceutical impurity reference standard with the molecular formula C14H20O3 and a molecular weight of 236.31 g/mol.
Structurally, Xylometazoline Impurity 9 (C14H20O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 236.31 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Xylometazoline Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H20O3 |
| Molecular Weight | 236.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Xylometazoline Standards
- Xylometazoline EP Impurity F (CAS 854646-92-7)
- Xylometazoline EP Impurity B (CAS 19387-83-8)
- Xylometazoline EP Impurity A (CAS 94266-17-8)
- Xylometazoline EP Impurity C (CAS 84803-57-6)
- Xylometazoline Impurity 8 (CAS 1260490-36-5)
- Xylometazoline EP Impurity A (CAS 81201-80-1)
- Xylometazoline EP Impurity E (CAS 104-15-4)
- Xylometazoline Impurity N1 (CAS 7364-19-4)
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