Xylometazoline EP Impurity E CAS 104-15-4
| CAS No. | 104-15-4 |
| Molecular Formula | C7H8O3S |
| Molecular Weight | 172.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Xylometazoline EP Impurity E (CAS 104-15-4), a pharmacopoeial impurity reference standard (molecular formula C7H8O3S, MW 172.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Xylometazoline EP Impurity E is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 172.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8O3S |
| Molecular Weight | 172.20 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Sulfur Atoms | 1 |
Related Xylometazoline Standards
- Xylometazoline Impurity N1 (CAS 7364-19-4)
- Xylometazoline EP Impurity C (CAS 84803-57-6)
- Xylometazoline EP Impurity B (CAS 19387-83-8)
- Xylometazoline EP Impurity F (CAS 854646-92-7)
- Xylometazoline Impurity 9 (CAS 1260490-37-6)
- Xylometazoline EP Impurity A (CAS 94266-17-8)
- Xylometazoline Impurity 8 (CAS 1260490-36-5)
- Xylometazoline EP Impurity A (CAS 81201-80-1)
Recommended Standards
- Meloxicam Impurity 11 (CAS 1865298-74-3)
- Iguratimod Impurity 11 (CAS 16156-59-5)
- Sulfadimethoxine EP Impurity E (CAS 63-74-1)
- 4-(Methylsulfonyl)-Phenol (CAS 14763-60-1)
- Paliperidone Impurity 42 (CAS CATO-C4X-1724142)
- Pivmecillinam Impurity 11 (CAS CATO-C4X-232311)
- Guanfacine Hydrochloride Impurity 3 (CAS 6575-24-2)
- N-(5,6-dihydrobenzo[h]quinazolin-2-yl)-4-methoxybenzamide (CAS 306979-32-8)
- ((Dimethylamino)(phenyl)methyl)phosphonic acid (CAS 67623-08-9)
- 4-bromo-2-[(trans-4-hydroxycyclohexyl)amino]benzonitrile (CAS 1008520-76-0)
- (R)-1-(2-bromo-5-fluorophenyl)ethan-1-ol (CAS 1232403-39-2)
- 1-(1h-Pyrrol-2-yl)-2-(p-tolylthio)ethan-1-one (CAS 794544-04-0)
- Hexahydro-7-methyl-1-(phenylmethyl)-1H-1,4-diazepine (CAS 1266843-37-1)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com