(2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid CAS 1383531-49-4
| CAS No. | 1383531-49-4 |
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid (CAS 1383531-49-4), molecular formula C12H10BFO2 and molecular weight 216.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid (C12H10BFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (2'-Fluoro-[1,1'-biphenyl]-4-yl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10BFO2 |
| Molecular Weight | 216.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Fluoro Standards
- (4-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1199616-73-3)
- (2-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 1218790-57-8)
- 2-Fluoro-biphenyl-5-ylboronic acid (CAS 1383532-12-4)
- (4'-Fluoro-[1,1'-biphenyl]-3-yl)boronic acid (CAS 159020-61-8)
- 2-Fluoro-4-biphenylylboronic acid (CAS 178305-99-2)
- (4'-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 179526-94-4)
- (4-Fluoro-[1,1'-biphenyl]-2-yl)boronic acid (CAS 2243975-77-9)
- 3-Fluoro-4-biphenylboronic acid (CAS 409108-13-0)
Recommended Standards
- (5-(Methylsulfonamido)pyridin-3-yl)boronic acid (CAS 1382475-73-1)
- 2-(2-Iodoethoxy)ethanol (CAS 130536-69-5)
- 5,7-Dichloropyrido[3,4-d]pyridazin-4(3H)-one (CAS 1390656-66-2)
- 4-(Sulfamoylamino)phenylboronic Acid (CAS 1298033-59-6)
- (6-Methoxypyrimidin-4-yl)methanamine hydrochloride (CAS 2306275-46-5)
- 2-((2,4-Dichlorophenyl)sulfonyl)ethan-1-ol (CAS 107737-90-6)
- 6-Fluoro-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole (CAS 864773-67-1)
- 4-Bromo-5-(difluoromethyl)-3-fluoropyridine-2-sulfonamide (CAS 1804854-90-7)
- 2,2-Diphenylcyclopropane-1-carbohydrazide (CAS 63070-28-0)
- N,N'-(Oxybis(ethane-2,1-diyl))bis(2-(3-hydroxy-2-oxopyridin-1(2H)-yl)acetamide) (CAS 2122211-48-5)
- CP-105,696 (CAS 158081-99-3)
- ethyl 2-(4-formyltriazol-1-yl)acetate (CAS 915370-02-4)
- 2,4-Dichloropyrimido[4,5-d]pyridazin-5(6H)-one (CAS 1638771-07-9)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com