5-(2,3-Difluorophenyl)-3-iodopyridin-2-amine CAS 1261446-72-3
| CAS No. | 1261446-72-3 |
| Molecular Formula | C11H7F2IN2 |
| Molecular Weight | 332.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(2,3-Difluorophenyl)-3-iodopyridin-2-amine (C11H7F2IN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(2,3-Difluorophenyl)-3-iodopyridin-2-amine (CAS 1261446-72-3), molecular formula C11H7F2IN2 and molecular weight 332.09 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(2,3-Difluorophenyl)-3-iodopyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H7F2IN2 |
| Molecular Weight | 332.09 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 1-[(3,4-Difluorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-73-4)
- 2-((3-(3,5-Difluorophenyl)-2-oxo-2h-chromen-7-yl)oxy)acetic acid (CAS 951999-09-0)
- 3-[(E)-2-[(2,4-Difluorophenyl)amino]-1-nitroethenyl]-1,3-dihydro-2-benzofuran-1-one (CAS 320420-45-9)
- N-(3,4-Difluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine (Dacomitinib Impurity) (CAS 2119689-75-5)
- Methyl 1-(2,4-Difluorophenyl)-3-(4-fluorophenyl)-1bromoh-pyrazole-5-carboxylate (CAS 1202029-46-6)
- 1-(2,4-Difluorophenyl)-N-(4-fluorophenyl)-5-methyl-1H-1,2,4-triazole-3-carboxamide (CAS 321431-58-7)
- (2,6-Difluorophenyl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone (CAS 260442-45-3)
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Recommended Standards
- Methyl 3-iodo-5-methoxy-2H-indazole-6-carboxylate (CAS 1227270-54-3)
- Ethyl 6-iodo-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-carboxylate (CAS 161468-54-8)
- 2-Bromo-6-(pentafluoroethylthio)benzonitrile (CAS 1159512-55-6)
- 3-Iodo-5,7-dimethoxy-4H-chromen-4-one (CAS 187877-91-4)
- 1-Phenylpiperidine-3-carboxamide (CAS 58971-08-7)
- Methyl 5-Bromo-4-methoxypyridine-2-carboxylate (CAS 1256789-95-3)
- 2-(Dipropylamino)isonicotinic acid (CAS 597564-11-9)
- (1R,3S)-3-(trifluoromethyl)cyclohexan-1-ol (CAS 205128-01-4)
- Methyl 2-((1-oxo-1-((2-(phenylthio)ethyl)amino)propan-2-yl)thio)benzoate (CAS 337923-57-6)
- 3-(2-Octyldodecyl)thiophene (CAS 1268060-76-9)
- Ethyl 2-methyl-2-(methylamino)propanoate (CAS 58743-30-9)
- 2-Aminobenzoic Acid Methyl Ester (CAS 134-20-3)
- 3-(Cyclopropylmethyl)-2-hydroxybenzaldehyde (CAS 1243476-39-2)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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