2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride CAS 1261453-16-0
| CAS No. | 1261453-16-0 |
| Molecular Formula | C7H4ClF3O3S |
| Molecular Weight | 260.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261453-16-0), molecular formula C7H4ClF3O3S and molecular weight 260.62 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H4ClF3O3S, 2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 260.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3O3S |
| Molecular Weight | 260.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
- 4-(Difluoromethoxy)-3-fluorobenzene-1-sulfonyl chloride (CAS 1178111-39-1)
- 3-(Difluoromethoxy)-2-fluorobenzene-1-sulfonyl chloride (CAS 1261677-89-7)
- 3-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261738-71-9)
- 2-(Difluoromethoxy)-3-fluorobenzene-1-sulfonyl chloride (CAS 1261760-49-9)
- 3-(Difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride (CAS 1261776-35-5)
- 4-(Difluoromethoxy)-2-fluorobenzene-1-sulfonyl chloride (CAS 1261825-39-1)
- 2-(difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride (CAS 1261862-25-2)
- 3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid (CAS 1710202-46-2)
Recommended Standards
- 3-Chloro-5-(trifluoromethyl)pyridine-2-sulfonamide (CAS 1249907-95-6)
- 2-hydroxy-5-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1261500-74-6)
- 4-Hydroxy-3-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1245457-03-7)
- 2-Hydroxy-4-(trifluoromethyl)benzenesulfonyl ChlorideDISCONTINUED (CAS 1261646-63-2)
- (E)-1,1,1,2-tetrafluoro-2-(perfluoropropoxy)oct-3-ene (CAS 261760-07-0)
- 3-methyl-N-[[(1R,2R)-2-allylcyclopropoxy]carbonyl]-L-valine compd. with (S)-1-Phenylethanamine (1:1) (CAS 1799733-54-2)
- 2-Aminoethyl methanethiosulfonate hydrochloride (CAS 37597-96-9)
- N-(2,4-Dimethoxyphenyl)-2-methoxybenzamide (CAS 314022-75-8)
- Propargyl-PEG2-Boc (CAS 1807503-80-5)
- 5-Bromo-1-isopropyl-3-nitropyridin-2(1H)-one (CAS 2738978-96-4)
- 1-(2-Propylpentanoyl)piperidine-3-carboxylic acid (CAS 183237-66-3)
- 4-(2-Chloro-4-ethylphenoxy)piperidinehydrochloride (CAS 1220020-19-8)
- 1,3-Dibromo-2-butoxy-5-isopropylbenzene (CAS 2379321-57-8)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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