3-(Difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride CAS 1261776-35-5
| CAS No. | 1261776-35-5 |
| Molecular Formula | C7H4ClF3O3S |
| Molecular Weight | 260.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 3-(Difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride (C7H4ClF3O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 260.62 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 3-(Difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride (CAS 1261776-35-5), a certified reference material (molecular formula C7H4ClF3O3S, MW 260.62 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3O3S |
| Molecular Weight | 260.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
- 4-(Difluoromethoxy)-3-fluorobenzene-1-sulfonyl chloride (CAS 1178111-39-1)
- 2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261453-16-0)
- 3-(Difluoromethoxy)-2-fluorobenzene-1-sulfonyl chloride (CAS 1261677-89-7)
- 3-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261738-71-9)
- 2-(Difluoromethoxy)-3-fluorobenzene-1-sulfonyl chloride (CAS 1261760-49-9)
- 4-(Difluoromethoxy)-2-fluorobenzene-1-sulfonyl chloride (CAS 1261825-39-1)
- 2-(difluoromethoxy)-5-fluorobenzene-1-sulfonyl chloride (CAS 1261862-25-2)
- 3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid (CAS 1710202-46-2)
Recommended Standards
- 2-Hydroxy-6-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1261752-22-0)
- 1-(2-chloro-4,6-difluoro-phenyl)hexahydropyrimidine-2,4-dione (CAS 1549287-66-2)
- 4-Chloro-3-(trifluoromethyl)benzenesulfonic acid (CAS 1644-79-7)
- 2-Hydroxy-3-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1261649-16-4)
- (R)-2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-1-ol (CAS 2505078-37-3)
- 5-(Tetrahydro-2H-pyran-4-yl)pyridin-3-amine (CAS 1259442-70-0)
- 2-(2-Chloroethyl-d (CAS 1252995-10-0)
- N’-Hydroxy-2-(4-pyridyl)acetimidamide (CAS 175532-12-4)
- [2,2'-Binaphthalene]-1,1'-diol (CAS 604-60-4)
- 5-Cyclobutyloxazole (CAS 2109553-33-3)
- 6-Chloro-4-fluoro-2-hydrazinylbenzo[d]thiazole (CAS 1177300-26-3)
- N-(4-Fluorobenzyl)-2-methylbutan-2-amine hydrochloride (CAS 1158628-76-2)
- 1-Bromo-2,5-dimethoxy-3,4,6-trimethylbenzene (CAS 69821-05-2)
- Dulaglutide (CAS 923950-08-7)
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