3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid CAS 1710202-46-2
| CAS No. | 1710202-46-2 |
| Molecular Formula | C9H6F2N2O3S |
| Molecular Weight | 260.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid (CAS 1710202-46-2) is a high-purity analytical reference standard with the molecular formula C9H6F2N2O3S and a molecular weight of 260.22 g/mol.
3-(Difluoromethoxy)-5-(1H-pyrazol-1-yl)thiophene-2-carboxylic acid (C9H6F2N2O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6F2N2O3S |
| Molecular Weight | 260.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Difluoromethoxy Standards
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- 2-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261453-16-0)
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- 3-(Difluoromethoxy)-4-fluorobenzenesulfonyl chloride (CAS 1261738-71-9)
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Recommended Standards
- 1-((6-Fluoroimidazo[1,2-a]pyridin-2-yl)methyl)-1H-imidazole-4-carboxylic acid (CAS 1708370-59-5)
- (2R,3S,4S,5R)-2,4,5,6-Tetrahydroxy-1-oxohexan-3-yl hydrogen sulfate (CAS 17112-77-5)
- 7-(3-Fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyrazine-3,8(2H,7H)-dione (CAS 1708178-72-6)
- 7-(2-Fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyrazine-3,8(2H,7H)-dione (CAS 1713713-91-7)
- 1-[(Pyridin-3-yl)methyl]-3-(thiophene-2-carbonyl)thiourea (CAS 351498-11-8)
- Organochlorine Pesticide Solution Mix-8 (CAS CATO-MCPD102108-HE)
- 2-(4-Methoxyphenyl)-N-(naphthalen-1-ylmethyl)ethan-1-amine (CAS 416889-35-5)
- 4-(2-Aminopropyl)-N,N-dimethylaniline (CAS 57580-63-9)
- 1-(1,3,5-Trimethyl-1H-pyrazol-4-yl)ethan-1-amine hydrochloride (CAS 1431964-36-1)
- N-benzyl-4-chloro-N-(2-oxo-2-((2,4,6-trichlorophenyl)amino)ethyl)benzamide (CAS 332163-67-4)
- Methyl 5-Amino-2-chlorobenzoate (CAS 42122-75-8)
- 2-(Pyrimidin-2-yl)-1,3-thiazole-4-carbaldehyde (CAS 1178019-16-3)
- Dapsone-d8(major) (CAS 557794-38-4)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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