2-Chloro-3-(difluoromethoxy)phenol CAS 1261478-68-5
| CAS No. | 1261478-68-5 |
| Molecular Formula | C7H5ClF2O2 |
| Molecular Weight | 194.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-3-(difluoromethoxy)phenol (CAS 1261478-68-5), molecular formula C7H5ClF2O2 and molecular weight 194.56 g/mol, is a CATO reference standard with documented purity and traceability.
2-Chloro-3-(difluoromethoxy)phenol (C7H5ClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-3-(difluoromethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5ClF2O2 |
| Molecular Weight | 194.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-3-(difluoromethoxy)phenol (CAS 1261440-11-2)
- 3-Chloro-4-(difluoromethoxy)phenol (CAS 1261604-72-1)
- 2-Chloro-4-(difluoromethoxy)phenol (CAS 88798-11-2)
- 6-Chloro-4-(difluoromethoxy)pyridin-2-amine (CAS 1677685-18-5)
- 2-Chloro-6-(difluoromethyl)pyrimidine-4,5-diamine (CAS 1706444-59-8)
- 5-Chloro-6-(difluoromethyl)-2-methylpyrimidin-4(3H)-one (CAS 1707378-61-7)
- 2-Chloro-5-(difluoromethoxy)-4-methylpyrimidine (CAS 1823916-35-3)
- 2-Chloro-2-oxoethane-1,1-diyl diacetate (CAS 36674-73-4)
Recommended Standards
- Lasmiditan Impurity 1 (CAS 79538-29-7)
- 2,4,5-trifluorobenzoylchloride (CAS 88419-56-1)
- 3-(2-Chloroethoxy)-1,1,2,2-tetrafluoropropane (CAS 64769-39-7)
- 2,3,5-trifluorobenzoyl chloride 2,3,5-tris(fluoranyl)benzoyl chloride 240800-48-0 A817075 (CAS 240800-48-0)
- 5-(4-Chlorophenylcarbamoyl)-2-fluorobenzeneboronic acid (CAS 1449132-34-6)
- 2-Chloro-4-(2,2,2-trifluoroethoxy)benzonitrile (CAS 183368-72-1)
- 2,5-Dibromo-3-thiophenecarbaldehyde (CAS 1193-69-7)
- 1-Isopropyl-3-methyl-1H-pyrazole-4,5-dione (CAS 197651-73-3)
- N-(5-vinylpyrazin-2-yl)pivalamide (CAS 710322-81-9)
- 3-(5-(2,4-Dichlorophenyl)-1,2,4-oxadiazol-3-yl)aniline (CAS 929338-51-2)
- (2-Methoxyphenyl)(phenyl)methanamine hydrochloride (CAS 5267-45-8)
- [3-(2-methoxyphenyl)-1,2-oxazol-5-yl]methanamine hydrochloride (CAS 1431962-29-6)
- 5-(4-Isopropylphenyl)-5-oxopentanoic acid (CAS 18847-18-2)
- Semaglutide impurity 100 (CAS CATO-C4X-2226100)
Why CATO?
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