4-(Difluoromethoxy)-2-fluoro-2'-(trifluoromethyl)-1,1'-biphenyl CAS 1261745-12-3
| CAS No. | 1261745-12-3 |
| Molecular Formula | C14H8F6O |
| Molecular Weight | 306.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Difluoromethoxy)-2-fluoro-2'-(trifluoromethyl)-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-(Difluoromethoxy)-2-fluoro-2'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261745-12-3), a certified reference material (molecular formula C14H8F6O, MW 306.20 g/mol) for analytical method development and quality control.
Structurally, 4-(Difluoromethoxy)-2-fluoro-2'-(trifluoromethyl)-1,1'-biphenyl (C14H8F6O) contains a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 306.20 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H8F6O |
| Molecular Weight | 306.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 4-(Difluoromethoxy)-2-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261440-14-5)
- 2-(Difluoromethoxy)-5-fluoro-4'-(trifluoromethyl)biphenyl (CAS 1261493-82-6)
- 4'-(Difluoromethoxy)-3'-fluoro-2-(trifluoromethyl)-1,1'-biphenyl (CAS 1261493-86-0)
- 2-(Difluoromethoxy)-3-fluoro-2'-(trifluoromethyl)biphenyl (CAS 1261771-25-8)
- 4-(Difluoromethoxy)-3-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261822-87-0)
- 2-(Difluoromethoxy)-5-fluoro-2'-(trifluoromethyl)biphenyl (CAS 1261887-76-6)
- 2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628442-57-8)
- 2-(4-(Difluoromethoxy)-2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628442-67-0)
Recommended Standards
- 3-{[(5-bromothiophen-2-yl)methyl]sulfanyl}-4-methyl-4,5-dihydro-1h-1,2,4-triazol-5-one (CAS 1248942-93-9)
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- 6-Bromo-2-(4-methylpiperazin-1-yl)quinoline (CAS 124783-03-5)
- 2-(4-Isopropyl-3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1305339-26-7)
- tert-Butyl (2-(2-chloro-2-phenylacetamido)ethyl)carbamate (CAS 1420800-29-8)
- 4-Bromo-1-(trifluoromethoxy)-2-(trifluoromethyl)benzene (CAS 933674-89-6)
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