2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 1628442-57-8
| CAS No. | 1628442-57-8 |
| Molecular Formula | C13H15BF4O3 |
| Molecular Weight | 306.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628442-57-8) is a high-purity analytical reference standard with the molecular formula C13H15BF4O3 and a molecular weight of 306.06 g/mol.
Structurally, 2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C13H15BF4O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.5, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 306.06 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(4-(Difluoromethoxy)-2,3-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H15BF4O3 |
| Molecular Weight | 306.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 2-(4-(Difluoromethoxy)-2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1628442-67-0)
- 3-Difluoromethoxy-2-bromomethyl-6-(trifluoromethyl)pyridine (CAS 1227513-70-3)
- 4-(Difluoromethoxy)-2-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261440-14-5)
- 2-(Difluoromethoxy)-5-fluoro-4'-(trifluoromethyl)biphenyl (CAS 1261493-82-6)
- 4'-(Difluoromethoxy)-3'-fluoro-2-(trifluoromethyl)-1,1'-biphenyl (CAS 1261493-86-0)
- 4-(Difluoromethoxy)-2-fluoro-2'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261745-12-3)
- 2-(Difluoromethoxy)-3-fluoro-2'-(trifluoromethyl)biphenyl (CAS 1261771-25-8)
- 4-(Difluoromethoxy)-3-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261822-87-0)
Recommended Standards
- 2-(3-Fluoro-4-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1622916-38-4)
- 2-Bromopyridin-3-yl trifluoromethanesulfonate (CAS 157373-97-2)
- 2,2-Dichloro-N-(1-(5-nitrofuran-2-yl)-1H-1,2,3-triazol-4-yl)acetamide (CAS 64082-38-8)
- 2-(4-Fluoro-3-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1366406-64-5)
- 2-(5H-Pyrrolo[2,3-b]pyrazin-7-yl)acetic acid (CAS 20322-09-2)
- 1-(3-Cyano-6-methylquinolin-4-yl)piperidine-4-carboxylic acid (CAS 1217180-17-0)
- 3-(1-Methyl-4-piperidinyl)phenol (CAS 105788-13-4)
- 1-(Furan-3-yl)propan-1-one (CAS 30078-67-2)
- 4-Amino-1-ethyl-N-(3-methoxypropyl)-1H-pyrazole-3-carboxamide (CAS 1490222-75-7)
- (s)-2-Amino-2-(2-(tert-butyl)phenyl)ethan-1-ol (CAS 1213302-89-6)
- 1-Oxaspiro[2.7]decane-2-carbonitrile (CAS 65445-51-4)
- 7-Isopropyl-3-methyl-1H-indole (CAS 94239-09-5)
- 479553-01-0 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid MFCD08272236 7-Azaindole-4-carboxylic acid (CAS 479553-01-0)
- Semaglutide Impurity 3 (CAS CATO-C4X-22263)
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