3-Methoxy-5-(trifluoromethoxy)phenol CAS 1261752-88-8
| CAS No. | 1261752-88-8 |
| Molecular Formula | C8H7F3O3 |
| Molecular Weight | 208.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Methoxy-5-(trifluoromethoxy)phenol (CAS 1261752-88-8) is a high-purity analytical reference standard with the molecular formula C8H7F3O3 and a molecular weight of 208.13 g/mol.
The molecular framework of 3-Methoxy-5-(trifluoromethoxy)phenol (C8H7F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Methoxy-5-(trifluoromethoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F3O3 |
| Molecular Weight | 208.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Methoxy Standards
- 3-Methoxy-4-(trifluoromethoxy)phenol (CAS 1261571-61-2)
- 2-Methoxy-4-(trifluoromethoxy)phenol (CAS 166312-49-8)
- 2-Methoxy-5-(trifluoromethoxy)phenol (CAS 895572-36-8)
- (5-Methoxy-3-(trifluoromethyl)pyrazin-2-yl)methanol (CAS 2770349-34-1)
- 5-Methoxy-3-methyl-4-nitro-1,2-benzoxazole (CAS 1435059-44-1)
- 2-(6-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)acetic acid (CAS 1785419-96-6)
- 6-Methoxy-5-nitroisoindolin-1-one (CAS 1822668-04-1)
- 2-(6-Methoxy-9H-purin-9-yl)acetic acid (CAS 6298-52-8)
Recommended Standards
- 4-(Hydroxymethyl)-2-(trifluoromethoxy)phenol (CAS 1261679-57-5)
- 2-(Hydroxymethyl)-5-(trifluoromethoxy)phenol (CAS 1261829-86-0)
- 3-(Hydroxymethyl)-4-(trifluoromethoxy)phenol (CAS 1261863-34-6)
- 4-(Hydroxymethyl)-3-(trifluoromethoxy)phenol (CAS 1232911-86-2)
- 2-Allyl-5-methylthiophene (CAS 69485-38-7)
- (3,5-Dimethoxyphenyl)(5-methylpyridin-2-yl)methanone (CAS 1187170-71-3)
- (4-((4-Methyl-1,4-diazepan-1-yl)methyl)phenyl)methanamine (CAS 884507-52-2)
- 2-Bromo-1-(1-methyl-1h-indol-3-yl)ethan-1-one (CAS 433335-72-9)
- 1-(5-(Trifluoromethyl)pyridin-3-yl)cyclopropane-1-carbonitrile (CAS 1427010-36-3)
- 2-Chloro-3-fluorophenyl diethylcarbamate (CAS 863870-76-2)
- Flurbiprofen Impurity 91 (CAS CATO-C4X-144491)
- 20654-88-0 Borane-11B, trifluoro- (11B)Boron trifluoride EINECS 243-946-1 (CAS 20654-88-0)
- 2-((7-Nitro-1H-benzo[d]imidazol-2-yl)thio)acetic acid (CAS 92824-09-4)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com