2-Methoxy-5-(trifluoromethoxy)phenol CAS 895572-36-8
| CAS No. | 895572-36-8 |
| Molecular Formula | C8H7F3O3 |
| Molecular Weight | 208.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 208.13 g/mol gives 2-Methoxy-5-(trifluoromethoxy)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Methoxy-5-(trifluoromethoxy)phenol (CAS 895572-36-8), molecular formula C8H7F3O3 and molecular weight 208.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2-Methoxy-5-(trifluoromethoxy)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Methoxy-5-(trifluoromethoxy)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7F3O3 |
| Molecular Weight | 208.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Methoxy Standards
- 3-Methoxy-4-(trifluoromethoxy)phenol (CAS 1261571-61-2)
- 3-Methoxy-5-(trifluoromethoxy)phenol (CAS 1261752-88-8)
- 2-Methoxy-4-(trifluoromethoxy)phenol (CAS 166312-49-8)
- (5-Methoxy-3-(trifluoromethyl)pyrazin-2-yl)methanol (CAS 2770349-34-1)
- 5-Methoxy-3-methyl-4-nitro-1,2-benzoxazole (CAS 1435059-44-1)
- 2-(6-Methoxy-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)acetic acid (CAS 1785419-96-6)
- 6-Methoxy-5-nitroisoindolin-1-one (CAS 1822668-04-1)
- 2-(6-Methoxy-9H-purin-9-yl)acetic acid (CAS 6298-52-8)
Recommended Standards
- 2-Ethyl-4-(trifluoromethyl)furan-3-carboxylic acid (CAS 2090983-17-6)
- 3,3,3-Trifluoro-2-(furan-2-ylmethyl)propanoic acid (CAS 241154-04-1)
- 1,2,3,4,5-Pentafluoro-6-(prop-1-en-2-yl)benzene (CAS 711-44-4)
- 3,6-Dinitro-1H-indazole (CAS 31163-64-1)
- Potassium 3-cyano-3-phenylacrylate (CAS 149373-58-0)
- Dibutyl 2-butoxysuccinate (CAS 63842-87-5)
- 5-chlorohexanoic acid (CAS 112176-22-4)
- 6-bromo-3-tert-butylimidazo[1,2-a]pyridine hydrobromide (CAS 1820673-81-1)
- 5-Bromo-6-fluoro-2-methylquinoline (CAS 80290-18-2)
- 7-Bromo-4-fluoro-1H-indole-3-carbaldehyde (CAS 1158416-77-3)
- Ticagrelor Impurity 112 (CAS CATO-C4X-1093112)
- 4-(N-Ethyl-N-2-Hydroxyethyl)-2-Methylphenylenediamine Sulfate (CAS 25646-77-9)
- 5-Bromo-1-tert-butyl-6-fluorobenzotriazole (CAS 1365271-86-8)
- Peptide Impurity 28 (CAS 1350456-64-2)
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