1-(2-Chloro-4-(difluoromethoxy)phenyl)propan-1-one CAS 1261776-30-0
| CAS No. | 1261776-30-0 |
| Molecular Formula | C10H9ClF2O2 |
| Molecular Weight | 234.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Chloro-4-(difluoromethoxy)phenyl)propan-1-one (C10H9ClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-(2-Chloro-4-(difluoromethoxy)phenyl)propan-1-one (CAS 1261776-30-0) is a high-purity analytical reference standard with the molecular formula C10H9ClF2O2 and a molecular weight of 234.63 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClF2O2 |
| Molecular Weight | 234.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-(2-Chloro-5-(difluoromethoxy)phenyl)propan-1-one (CAS 1261478-73-2)
- 1-(2-Chloro-3-(difluoromethoxy)phenyl)propan-1-one (CAS 1261821-25-3)
- Ethyl 4-Chloro-alpha,alpha-difluorophenylacetate (CAS 130754-19-7)
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- 3-(5-Chloro-2-(difluoromethoxy)phenyl)prop-2-en-1-ol (CAS 1564052-04-5)
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Recommended Standards
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