2-Chloro-4-(difluoromethoxy)-3'-(trifluoromethoxy)-1,1'-biphenyl CAS 1261777-47-2
| CAS No. | 1261777-47-2 |
| Molecular Formula | C14H8ClF5O2 |
| Molecular Weight | 338.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-Chloro-4-(difluoromethoxy)-3'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261777-47-2), a certified reference material (molecular formula C14H8ClF5O2, MW 338.66 g/mol) for analytical method development and quality control.
2-Chloro-4-(difluoromethoxy)-3'-(trifluoromethoxy)-1,1'-biphenyl (C14H8ClF5O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF5O2 |
| Molecular Weight | 338.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-3-(difluoromethoxy)-4'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261507-48-5)
- 4'-Chloro-3'-(difluoromethoxy)-2-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261583-53-2)
- 4-Chloro-2-(difluoromethoxy)-2'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261777-55-2)
- 2-Chloro-4-(difluoromethoxy)-4'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261828-96-9)
- 2-Chloro-5-(difluoromethoxy)-2'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261837-33-5)
- 2-Chloro-3-(difluoromethoxy)-4'-(trifluoromethoxy)-1,1'-biphenyl (CAS 1261865-89-7)
- 2-(2-Chloro-4-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244084-86-2)
- 2-(5-Chloro-2-methoxyphenoxy)-1,3-difluoro-5-(trifluoromethyl)benzene (CAS 2244086-53-9)
Recommended Standards
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(4-chlorophenyl)thiophen-2-yl)boronate (CAS 1162204-77-4)
- N-Tetracosane (CAS 646-31-1)
- 2-Chloro-N-(phenylcarbamoselenoyl)nicotinamide (CAS 89914-52-3)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(4-chlorophenyl)thiophen-2-yl)boronate (CAS 1402227-79-5)
- 4-[1-(Boc-amino)cyclobutyl]aniline (CAS 1259224-00-4)
- Isooctyl acrylate,contains 75-125 ppm monomethyl ether hydroquinone as inhibitor (CAS 29590-42-9)
- Diformylimide sodium salt (CAS 18197-26-7)
- 1-Methyl-1,2,3-triazole-5-boronic Acid Pinacol Ester (CAS 1047636-97-4)
- (Pyrrolidin-1-yl)acetic acid hydrochloride (CAS 6628-74-6)
- 4-Amino-3H-imidazo[4,5-c]pyridine (CAS 6811-77-4)
- (2E)-3-(4-Chlorophenyl)-1-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]prop-2-en-1-one (CAS 1430415-76-1)
- 4'-Ethyl-4-hydroxy-[1,1'-biphenyl]-3-carbaldehyde (CAS 1111120-97-8)
- 4,5-Dichloro-3-iodo-1H-indazole (CAS 2586127-25-3)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
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