2-(Difluoromethoxy)-4-fluoro-1-iodobenzene CAS 1261781-73-0
| CAS No. | 1261781-73-0 |
| Molecular Formula | C7H4F3IO |
| Molecular Weight | 288.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-(Difluoromethoxy)-4-fluoro-1-iodobenzene (C7H4F3IO) contains a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 288.01 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(Difluoromethoxy)-4-fluoro-1-iodobenzene (CAS 1261781-73-0), a certified reference material (molecular formula C7H4F3IO, MW 288.01 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4F3IO |
| Molecular Weight | 288.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/I-containing |
Related Difluoromethoxy Standards
- 4-(Difluoromethoxy)-2-fluoro-1-iodobenzene (CAS 1261478-98-1)
- 1-(Difluoromethoxy)-2-fluoro-4-iodobenzene (CAS 1261500-62-2)
- 2-(Difluoromethoxy)-1-fluoro-4-iodobenzene (CAS 1261572-00-2)
- 1-(Difluoromethoxy)-3-fluoro-5-iodobenzene (CAS 1261583-29-2)
- 1-(Difluoromethoxy)-3-fluoro-2-iodobenzene (CAS 1261606-77-2)
- 1-(Difluoromethoxy)-2-fluoro-3-iodobenzene (CAS 1261648-85-4)
- 4-(Difluoromethoxy)-1-fluoro-2-iodobenzene (CAS 1261676-10-1)
- 2-(Difluoromethoxy)-1-fluoro-3-iodobenzene (CAS 1261763-19-2)
Recommended Standards
- 1-(Difluoromethoxy)-4-fluoro-2-iodobenzene (CAS 1261827-29-5)
- 5-Iodo-4-(trifluoromethyl)pyridin-2-amine (CAS 1321530-57-7)
- 6-Iodo-2-trifluoromethylphenol (CAS 149209-48-3)
- 2-(Trifluoromethoxy)iodobenzene (CAS 175278-00-9)
- 4-(Difluoromethyl)-3-hydroxy-5-methylpyridine-2-sulfonyl chloride (CAS 1805603-54-6)
- 1-Ethylisoindoline hydrochloride (CAS 2137530-76-6)
- Ethyl 2-(4-(3-(4-(tosyloxy)butoxy)propoxy)butoxy)acetate (CAS 2681388-10-1)
- 2-Ethyl-4-(((2-methylthiazol-4-yl)methyl)thio)-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine (CAS 690643-70-0)
- 2-Amino-1-(3,4-dihydroquinolin-1(2H)-yl)-3-methylbutan-1-one hydrochloride (CAS 1246172-76-8)
- 4-Methoxy-3-nitro-N-phenylbenzamide (CAS 97-32-5)
- N-((tetrahydro-2H-pyran-4-yl)methyl)cyclohexanamine (CAS 1250562-92-5)
- Clonidine EP Impurity C (CAS 608-31-1)
- Testosterone Enantate EP Impurity G (CAS 119698-27-0)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
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